Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Circular RNAs (circRNAs) are a novel class of non-coding RNAs. They are single-stranded
RNA transcripts characterized with a closed loop structure making them resistant to …

Alzheimer's disease (AD) is one of the most common neurodegenerative disorders
associated with age or inherited mutations. It is characterized by severe dementia in the late …

The signal recognition particle (SRP) is a ribonucleoprotein complex with dual functions. It
co-translationally targets proteins with a signal sequence to the endoplasmic reticulum (ER) …

The endoplasmic reticulum (ER) is central to the processing of luminal, transmembrane, and
secretory proteins, and maintaining a functional ER is essential for organismal physiology …

Abstract Regulation of Aberrant Protein Production (RAPP) is a protein quality control in
mammalian cells. RAPP degrades mRNAs of nascent proteins not able to associate with …

The pervasiveness and mortality associated with methamphetamine abuse have doubled
during the past decade, suggesting a possible worldwide substance use crisis. Epitomizing …

Cells synthesize thousands of different proteins that should be delivered to different cellular
compartments, integrated into membranes, or secreted outside of the cell to conduct their …

Parkinson's disease (PD) is characterized by dopaminergic neurodegeneration and an
abnormal accumulation of α-synuclein aggregates. A number of genetic factors have been …

Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by the
progressive degeneration of dopaminergic neurons in the substantia nigra region of the …