Combating oxidative stress and inflammation in COVID‐19 by molecular hydrogen therapy: mechanisms and perspectives

D Alwazeer, FFC Liu, XY Wu… - Oxidative medicine and …, 2021‏ - Wiley Online Library
COVID‐19 is a widespread global pandemic with nearly 185 million confirmed cases and
about four million deaths. It is caused by an infection with the severe acute respiratory …

Advances in the pathogenesis and prevention of contrast-induced nephropathy

F Zhang, Z Lu, F Wang - Life sciences, 2020‏ - Elsevier
With the increasing application of medical imaging contrast materials, contrast-induced
nephropathy has become one of the leading causes of iatrogenic renal insufficiency. The …

Contrast-induced nephropathy and oxidative stress: mechanistic insights for better interventional approaches

P Kusirisin, SC Chattipakorn, N Chattipakorn - Journal of translational …, 2020‏ - Springer
Contrast-induced nephropathy (CIN) or contrast-induced acute kidney injury (CI-AKI) is an
iatrogenic acute kidney injury observed after intravascular administration of contrast media …

Advances in predictive in vitro models of drug-induced nephrotoxicity

JYC Soo, J Jansen, R Masereeuw… - Nature Reviews …, 2018‏ - nature.com
In vitro screens for nephrotoxicity are currently poorly predictive of toxicity in humans.
Although the functional proteins that are expressed by nephron tubules and mediate drug …

Contrast-induced acute kidney injury: a review of definition, pathogenesis, risk factors, prevention and treatment

Y Li, J Wang - BMC nephrology, 2024‏ - Springer
Contrast-induced acute kidney injury (CI-AKI) has become the third leading cause of
hospital-acquired AKI, which seriously threatens the health of patients. To date, the precise …

A review of phenformin, metformin, and imeglimin

R Yendapally, D Sikazwe, SS Kim… - Drug development …, 2020‏ - Wiley Online Library
Diabetes mellitus is a serious metabolic disorder affecting millions of people worldwide.
Phenformin and metformin are biguanide antidiabetic agents that are conveniently …

Renalase contributes to protection against renal fibrosis via inhibiting oxidative stress in rats

Y Wu, L Wang, X Wang, Y Wang, Q Zhang… - International urology and …, 2018‏ - Springer
Background Renal interstitial fibrosis (RIF) is a common pathway for progression of chronic
kidney disease (CKD) to end-stage renal disease. In our previous study, it has been …

Dapagliflozin attenuates contrast-induced acute kidney injury by regulating the HIF-1α/HE4/NF-κB pathway

X Huang, X Guo, G Yan, Y Zhang, Y Yao… - Journal of …, 2022‏ - journals.lww.com
Contrast-induced acute kidney injury (CI-AKI) causes clinically acquired nephropathy in
patients who undergo coronary interventions. Hypoxic injury to proximal tubular epithelial …

[PDF][PDF] Contrast-induced nephropathy: a review of mechanisms and risks

E Shams, HN Mayrovitz - Cureus, 2021‏ - cureus.com
Radiological procedures utilizing intravenous iodinated contrast agents are being widely
utilized for both therapeutic and diagnostic purposes. This has resulted in an increasing …

Contrast-induced acute kidney injury: review and practical update

R Morcos, M Kucharik, P Bansal… - Clinical Medicine …, 2019‏ - journals.sagepub.com
Contrast-induced acute kidney injury (CI-AKI) is an important consideration in patients
undergoing cardiac catheterization. There has been a continuous strive to decrease …