With the rapid explosion of genomic sequence databases, there has been an equivalent
boom in genomics, the use of sequence information to define and compare gene families …

Lectins, or carbohydrate binding proteins, recognize specific oligosaccharide structures on
glycoproteins and glycolipids. Several families of animal lectins have been identified; for …

Galectins belong to a family of carbohydrate-binding proteins with an affinity for β-
galactosides. Galectin-1 is differentially expressed by various normal and pathologic tissues …

The basis for the endothelial cell-restricted expression of endothelial nitric-oxide synthase
(eNOS) is not known. While transgenic promoter/reporter mice demonstrated endothelium …

Regulation of gene expression in mammals through methylation of cytosine residues at CpG
dinucleotides is involved in the development and progression of tumors. Because many …

Objective To characterize the expression pattern and role of galectin 3 and galectin 3
binding protein (G3BP) in rheumatoid arthritis (RA), in comparison with galectin 1, and to …

Galectins are a large family of carbohydrate binding proteins with members in nearly every
lineage of multicellular life. Through tandem and en-mass genome duplications, over 15 …

Fourteen members of the galectin family, proteins with conserved carbohydrate-recognition
domains that bind β-galactoside, have been cloned and more are expected to be discovered …

The first studies suggesting that abnormal expression of galectins is associated with cancer
were published more than 30 years ago. Today, the role of galectins in cancer is relatively …

In this review we have summarized the more recent studies on the expression of mammalian
galectins. One interesting observation that can be made is that in most of microarrays and/or …