[HTML][HTML] SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

Multisystem inflammatory syndrome in children and Kawasaki disease: a critical comparison

C Sharma, M Ganigara, C Galeotti, J Burns… - Nature Reviews …, 2021 - nature.com
Children and adolescents infected with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are predominantly asymptomatic or have mild symptoms compared with the …

Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children

D Lee, J Le Pen, A Yatim, B Dong, Y Aquino, M Ogishi… - Science, 2022 - science.org
Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe condition that
follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or …

Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

K Sacco, R Castagnoli, S Vakkilainen, C Liu… - Nature medicine, 2022 - nature.com
Abstract Pediatric Coronavirus Disease 2019 (pCOVID-19) is rarely severe; however, a
minority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS …

Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine–associated myocarditis

A Barmada, J Klein, A Ramaswamy, NN Brodsky… - Science …, 2023 - science.org
Rare immune-mediated cardiac tissue inflammation can occur after vaccination, including
after SARS-CoV-2 mRNA vaccines. However, the underlying immune cellular and molecular …

Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC)

S Mohandas, P Jagannathan, TJ Henrich, ZA Sherif… - Elife, 2023 - elifesciences.org
With a global tally of more than 500 million cases of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections to date, there are growing concerns about the post …

Immunology of SARS-CoV-2 infection in children

J Chou, PG Thomas, AG Randolph - Nature immunology, 2022 - nature.com
Children and adolescents exhibit a broad range of clinical outcomes from SARS-CoV-2
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …

The microbe, the infection enigma, and the host

JL Casanova, L Abel - Annual Review of Microbiology, 2024 - annualreviews.org
Human infectious diseases are unique in that the discovery of their environmental trigger,
the microbe, was sufficient to drive the development of extraordinarily effective principles …

Multisystem inflammatory syndrome in children and long COVID: the SARS-CoV-2 viral superantigen hypothesis

M Noval Rivas, RA Porritt, MH Cheng, I Bahar… - Frontiers in …, 2022 - frontiersin.org
Multisystem inflammatory syndrome in children (MIS-C) is a febrile pediatric inflammatory
disease that may develop weeks after initial SARS-CoV-2 infection or exposure. MIS-C …

[HTML][HTML] SARS-CoV-2 infections in children: Understanding diverse outcomes

P Brodin - Immunity, 2022 - cell.com
SARS-CoV-2 infections mostly lead to mild or even asymptomatic infections in children, but
the reasons for this are not fully understood. More efficient local tissue responses, better …