Schlafens can put viruses to sleep

ET Kim, MD Weitzman - Viruses, 2022 - mdpi.com
The Schlafen gene family encodes for proteins involved in various biological tasks, including
cell proliferation, differentiation, and T cell development. Schlafens were initially discovered …

Post-translational polymodification of b1-tubulin regulates motor protein localization in platelet production and function

AO Khan, A Slater, A Maclachlan… - …, 2020 - pmc.ncbi.nlm.nih.gov
In specialized cells, the expression of specific tubulin isoforms and their subsequent post-
translational modifications drive and coordinate unique morphologies and behaviors. The …

Heterozygous mutation SLFN14 K208N in mice mediates species-specific differences in platelet and erythroid lineage commitment

RJ Stapley, CW Smith, EJ Haining, A Bacon… - Blood …, 2021 - ashpublications.org
Abstract Schlafen 14 (SLFN14) has recently been identified as an endoribonuclease
responsible for cleaving RNA to regulate and inhibit protein synthesis. Early studies …

Identification of a pathogenic TUBB1 variant in a Chinese family with congenital macrothrombocytopenia through whole genome sequencing

Y Hou, L Shao, H Zhou, Y Liu, DG Fisk, E Spiteri… - Platelets, 2021 - Taylor & Francis
Congenital macrothrombocytopenia is a genetically heterogeneous group of rare disorders.
We herein report a large Chinese family presented with phenotypic variability involving …

[PDF][PDF] Schlafens Can Put Viruses to Sleep. Viruses 2022, 14, 442

ET Kim, MD Weitzman - 2022 - med.upenn.edu
The Schlafen gene family encodes for proteins involved in various biological tasks, including
cell proliferation, differentiation, and T cell development. Schlafens were initially discovered …

Investigating the role of SLFN14 mutations in inherited thrombocytopenia and haematopoiesis

RJ Stapley - 2021 - etheses.bham.ac.uk
Schlafen 14 (SLFN14) has recently been identified as an endoribonuclease responsible for
cleaving RNA to regulate and inhibit protein synthesis. Early studies revealed members of …

[PDF][PDF] Post-translational polymodification of ß1-tubulin regulates motor protein localisation in platelet production and function

AO Khan, A Slater, A Maclachlan, PLR Nicolson… - academia.edu
In specialised cells, the expression of specific tubulin isoforms and their subsequent post-
translational modifications drive and coordinate unique morphologies and behaviours. The …