Biomolecular condensates and disease pathogenesis

K Ruan, G Bai, Y Fang, D Li, T Li, X Liu, B Lu… - Science China Life …, 2024 - Springer
Biomolecular condensates or membraneless organelles (MLOs) formed by liquid-liquid
phase separation (LLPS) divide intracellular spaces into discrete compartments for specific …

Biomolecular condensates: structure, functions, methods of research

NA Gorsheneva, JV Sopova, VV Azarov, AV Grizel… - Biochemistry …, 2024 - Springer
The term “biomolecular condensates” is used to describe membraneless compartments in
eukaryotic cells, accumulating proteins and nucleic acids. Biomolecular condensates are …

Emerging experimental methods to study the thermodynamics of biomolecular condensate formation

S Ray, AK Buell - The Journal of Chemical Physics, 2024 - pubs.aip.org
The formation of biomolecular condensates in vivo is increasingly recognized to underlie a
multitude of crucial cellular functions. Furthermore, the evolution of highly dynamic protein …

Sensitized Emission Imaging Allows Nanoscale Surface Polarity Map** of α-Synuclein Amyloid Fibrils

J Mahato, R Mukherjee, A Bose, S Mehra… - ACS Chemical …, 2023 - ACS Publications
When misfolded, α-Synuclein (α-Syn), a natively disordered protein, aggregates to form
amyloid fibrils responsible for the neurodegeneration observed in Parkinson's disease …

[PDF][PDF] БИОМОЛЕКУЛЯРНЫЕ КОНДЕНСАТЫ: СТРУКТУРА, ФУНКЦИИ, МЕТОДЫ ИЗУЧЕНИЯ

НА ГОРШЕНЕВА, ЮВ СОПОВА, ВВ АЗАРОВ… - researchgate.net
Один из способов обеспечить высокую скорость и специфичность хими ческих реакций
в клетке–компартментализация ферментов и их мишеней. Традиционно, под …