Bufadienolides preferentially inhibit aminopeptidase N among mammalian metallo-aminopeptidases; relationship with effects on human melanoma MeWo cells
Bufadienolides are steroids that inhibit Na+/K+-ATPase; recent evidence shows that bufalin
inhibits the activity of porcine aminopeptidase N (pAPN). We evaluated the selectivity of …
inhibits the activity of porcine aminopeptidase N (pAPN). We evaluated the selectivity of …
Bestatin and bacitracin inhibit porcine kidney cortex dipeptidyl peptidase IV activity and reduce human melanoma MeWo cell viability
LR Méndez, Y Arrebola, ME Valdés-Tresanco… - International Journal of …, 2020 - Elsevier
Bestatin and bacitracin are inhibitors of metallo aminopeptidases and bacterial proteases.
However, their effects on other human peptidases, like dipeptidyl peptidase IV (DPP-IV, EC …
However, their effects on other human peptidases, like dipeptidyl peptidase IV (DPP-IV, EC …
Effect of non-competitive inhibitors of aminopeptidase N on viability of human and murine tumor cells
I Pascual Alonso, G García, L Díaz… - Pure and Applied …, 2021 - degruyter.com
Cancer is the second leading cause of death worldwide. Peptidases participate in tumor
development and growth. Mammalian neutral aminopeptidase (APN, EC 3.4. 11.2, M1 …
development and growth. Mammalian neutral aminopeptidase (APN, EC 3.4. 11.2, M1 …
Bacillus licheniformis: A Producer of Antimicrobial Substances, including Antimycobacterials, Which Are Feasible for Medical Applications
MO Shleeva, DA Kondratieva, AS Kaprelyants - Pharmaceutics, 2023 - mdpi.com
Bacillus licheniformis produces several classes of antimicrobial substances, including
bacteriocins, which are peptides or proteins with different structural composition and …
bacteriocins, which are peptides or proteins with different structural composition and …
Marine Invertebrates: A Promissory Still Unexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families
Proteolytic enzymes, also known as peptidases, are critical in all living organisms.
Peptidases control the cleavage, activation, turnover, and synthesis of proteins and regulate …
Peptidases control the cleavage, activation, turnover, and synthesis of proteins and regulate …
Bufotalin inhibits porcine kidney cortex aminopeptidase N and is cytotoxic to APN+ tumor cells
F Almeida García, L Rivera Méndez… - Pure and Applied …, 2023 - degruyter.com
Bufadienolides are steroids that inhibit the Na+/K+ ATPase pump. Recent studies show that
members of the bufadienolide family also inhibit the activity of aminopeptidase N (APN) …
members of the bufadienolide family also inhibit the activity of aminopeptidase N (APN) …
Mammalian aminopeptidase A: biochemical characteristics, physiological roles and physiopathological implications
I Pascual Alonso, Y Arrebola Sánchez… - Pure and Applied …, 2023 - degruyter.com
Aminopeptidases selectively hydrolyze an aminoacid residue from the amino terminus of
proteins and peptides resulting in their activation or inactivation. These enzymes are mainly …
proteins and peptides resulting in their activation or inactivation. These enzymes are mainly …
[PDF][PDF] Bestatin is a non-competitive inhibitor of porcine M1 family glutamyl aminopeptidase: insights for selective inhibitor design
ME Valdés-Tresanco, YA Sánchez, LR Méndez… - 2021 - academia.edu
Glutamyl aminopeptidase (APA) is an M1 family membrane-bound ectoenzyme that is a
target for the development of antihypertensive and anticancer agents. Bestatin is a natural …
target for the development of antihypertensive and anticancer agents. Bestatin is a natural …
Bacillus licheniformis–A Perspective for Medical Applications Producer of Variety of Antimicrobial Substances Including Antimycobacterials
M Shleeva, D Kondrateva, A Kaprelyants - 2023 - preprints.org
Bacillus licheniformis produce several classes of antimicrobial substances which are mainly
either peptides or proteins. Among of them bacteriocins-peptides or proteins of different …
either peptides or proteins. Among of them bacteriocins-peptides or proteins of different …
[HTML][HTML] BAY73-4506 Inhibitor. com
LR Méndez, Y Arrebola, ME Valdés-Tresanco… - bay73-4506inhibitor.com
abstract Bestatin and bacitracin are inhibitors of metallo aminopeptidases and bacterial
proteases. However, their effects on other human peptidases, like dipeptidyl peptidase IV …
proteases. However, their effects on other human peptidases, like dipeptidyl peptidase IV …