Post-transplant diabetes mellitus (PTDM) is a frequent consequence of solid organ
transplantation. PTDM has been associated with greater mortality and increased infections …

The complement cascade, traditionally considered an effector arm of innate immunity
required for host defense against pathogens, is now recognized as a crucial pathogenic …

Using meta-analysis of eight independent transplant datasets (236 graft biopsy samples)
from four organs, we identified a common rejection module (CRM) consisting of 11 genes …

The complement system is a key element of the innate immune system, and the production
of complement components can be divided into central (hepatic) and peripheral …

In as many as 50% of cases the immediate post-kidney transplant course is complicated by
delayed graft function that is most commonly related to ischemia and reperfusion injury. In …

Percutaneous needle core biopsy is the definitive procedure by which essential diagnostic
and prognostic information on acute and chronic renal allograft dysfunction is obtained. The …

The complement system is a major component of innate immunity and has been commonly
identified as a central element in host defense, clearance of immune complexes, and tissue …

Background In the last few decades, strategies to improve allograft survival after kidney
transplantation have been directed to recipient-dependent mechanisms of renal injury. In …

Interstitial fibrosis and tubular atrophy (IFTA) is found in approximately 25% of 1‐year
biopsies posttransplant. It is known that IFTA correlates with decreased graft survival when …

It is of particular importance in kidney transplantation to understand the underlying
mechanisms and effects of ischemia/reperfusion on the graft as this knowledge also opens …