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Pathophysiology of systemic sclerosis: current understanding and new insights
ABSTRACT Introduction: Systemic sclerosis (SSc) is a complex autoimmune connective
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …
Pathogenesis of systemic sclerosis
D Pattanaik, M Brown, BC Postlethwaite… - Frontiers in …, 2015 - frontiersin.org
Systemic scleroderma (SSc) is one of the most complex systemic autoimmune diseases. It
targets the vasculature, connective tissue-producing cells (namely fibroblasts/myofibroblasts …
targets the vasculature, connective tissue-producing cells (namely fibroblasts/myofibroblasts …
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
Fibroproliferative diseases, including the pulmonary fibroses, systemic sclerosis, liver
cirrhosis, cardiovascular disease, progressive kidney disease, and macular degeneration …
cirrhosis, cardiovascular disease, progressive kidney disease, and macular degeneration …
Inflammation, growth factors, and pulmonary vascular remodeling
Inflammatory processes are prominent in various types of human and experimental
pulmonary hypertension (PH) and are increasingly recognized as major pathogenic …
pulmonary hypertension (PH) and are increasingly recognized as major pathogenic …
The role of endothelial cells in the vasculopathy of systemic sclerosis: a systematic review
Abstract Introduction Systemic sclerosis (SSc) is an autoimmune connective tissue disorder
characterized by fibroproliferative vasculopathy, immunological abnormalities and …
characterized by fibroproliferative vasculopathy, immunological abnormalities and …
Systemic sclerosis: an update in 2016
Systemic sclerosis (SSc) is a chronic immune disorder of unknown origin, dominated by
excessive fibrosis responsible for cutaneous and pulmonary fibrosis, and by vascular …
excessive fibrosis responsible for cutaneous and pulmonary fibrosis, and by vascular …
Neurologic involvement in scleroderma: a systematic review
TN Amaral, FA Peres, AT Lapa… - Seminars in Arthritis and …, 2013 - Elsevier
abstract Objectives To perform a systematic review of neurologic involvement in Systemic
sclerosis (SSc) and Localized Scleroderma (LS), describing clinical features, neuroimaging …
sclerosis (SSc) and Localized Scleroderma (LS), describing clinical features, neuroimaging …
[HTML][HTML] Endothelial dysfunction in systemic sclerosis
E Patnaik, M Lyons, K Tran, D Pattanaik - International Journal of …, 2023 - mdpi.com
Systemic sclerosis, commonly known as scleroderma, is an autoimmune disorder
characterized by vascular abnormalities, autoimmunity, and multiorgan fibrosis. The exact …
characterized by vascular abnormalities, autoimmunity, and multiorgan fibrosis. The exact …
Vasculopathy in scleroderma
Y Asano, S Sato - Seminars in immunopathology, 2015 - Springer
Systemic sclerosis (SSc) is a multisystem connective tissue disorder featured by vascular
injury and fibrosis of the skin and various internal organs with autoimmune background …
injury and fibrosis of the skin and various internal organs with autoimmune background …
Capillaroscopy
Capillaroscopy is the most reliable way to distinguish between primary and secondary
Raynaud's phenomenon (RP) through identification of an early pattern of systemic sclerosis …
Raynaud's phenomenon (RP) through identification of an early pattern of systemic sclerosis …