This review is aimed at presenting the state-of-the-art of time domain (TD) functional near-
infrared spectroscopy (fNIRS). We first introduce the physical principles, the basics of …

The recent developments in time-domain diffuse optics that rely on physical concepts (eg,
time-gating and null distance) and advanced photonic components (eg, vertical cavity …

Cerebral blood flow (CBF) is crucial for brain health. Speckle contrast optical spectroscopy
(SCOS) is a technique that has been recently developed to measure CBF, but the use of …

A multi-center study has been set up to accurately characterize the optical properties of
diffusive liquid phantoms based on Intralipid and India ink at near-infrared (NIR) …

Performance assessment of instruments devised for clinical applications is of key
importance for validation and quality assurance. Two new protocols were developed and …

Near-infrared (NIR) fluorescent probes offer advantages of high photon penetration, reduced
light scattering and minimal autofluorescence from living tissues, rendering them valuable …

Direct assessment of blood oxygenation in the human placenta can provide information
about placental function. However, the monitoring of placental oxygenation involves …

The purpose of this study was to assess the accuracy of absolute cerebral blood flow (CBF)
measurements obtained by dynamic contrast-enhanced (DCE) near-infrared spectroscopy …

We present an overview of the wide range of potential applications of optical methods for
monitoring traumatic brain injury. The MEDLINE database was electronically searched with …

Quantum dots (QDs) are attractive photoluminescence probes for biomedical imaging due to
their unique photophysical properties. However, the potential toxicity of QDs has remained a …