Tumor-infiltrating lymphocytes for treatment of solid tumors: It takes two to tango?

MH Kazemi, M Sadri, A Najafi, A Rahimi… - Frontiers in …, 2022 - frontiersin.org
Tumor-infiltrating lymphocytes (TILs), frontline soldiers of the adaptive immune system, are
recruited into the tumor site to fight against tumors. However, their small number and …

[HTML][HTML] Unveiling the immune microenvironment's role in breast cancer: A glimpse into promising frontiers

A Kotsifaki, N Alevizopoulos, V Dimopoulou… - International journal of …, 2023 - mdpi.com
Breast cancer (BC), one of the most widespread and devastating diseases affecting women
worldwide, presents a significant public health challenge. This review explores the emerging …

Smart composite scaffold to synchronize magnetic hyperthermia and chemotherapy for efficient breast cancer therapy

R Sun, H Chen, M Wang, T Yoshitomi, M Takeguchi… - Biomaterials, 2024 - Elsevier
Combination of different therapies is an attractive approach for cancer therapy. However, it is
a challenge to synchronize different therapies for maximization of therapeutic effects. In this …

Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective …

AKMH Morshed, S Al Azad, MAR Mia, MF Uddin… - Molecular Diversity, 2023 - Springer
The HER2-positive patients occupy~ 30% of the total breast cancer patients globally where
no prevalent drugs are available to mitigate the frequent metastasis clinically except …

Nanomedicine-based drug-targeting in breast cancer: pharmacokinetics, clinical progress, and challenges

M Rahman, O Afzal, SNMN Ullah, MY Alshahrani… - ACS …, 2023 - ACS Publications
Breast cancer (BC) is a malignant neoplasm that begins in the breast tissue. After skin
cancer, BC is the second most common type of cancer in women. At the end of 2040, the …

Current progress and challenges of immunotherapy in gastric cancer: A focus on CAR-T cells therapeutic approach

M Entezam, MJ Sanaei, Y Mirzaei, AH Mer… - Life sciences, 2023 - Elsevier
Gastric cancer (GC) is a severe malignancy, accounting for the third most common cancer
death worldwide. Despite the development of chemo-radiation therapy, there has not been …

Chemotherapy reinforces anti-tumor immune response and enhances clinical efficacy of immune checkpoint inhibitors

L Zhang, C Zhou, S Zhang, X Chen, J Liu, F Xu… - Frontiers in …, 2022 - frontiersin.org
New evidence suggests that the clinical success of chemotherapy is not merely due to tumor
cell toxicity but also arises from the restoration of immunosurveillance, which has been …

Multiplex immunofluorescence and the digital image analysis workflow for evaluation of the tumor immune environment in translational research

F Rojas, S Hernandez, R Lazcano… - Frontiers in …, 2022 - frontiersin.org
A robust understanding of the tumor immune environment has important implications for
cancer diagnosis, prognosis, research, and immunotherapy. Traditionally …

Advances in immunotherapy for breast cancer and feline mammary carcinoma: From molecular basis to novel therapeutic targets

T Vilela, S Valente, J Correia, F Ferreira - Biochimica et Biophysica Acta …, 2024 - Elsevier
The role of inflammation in cancer is a topic that has been investigated for many years. As
established, inflammation emerges as a defining characteristic of cancer, presenting itself as …

Personalized immunotherapy in colorectal cancers: where do we stand?

LF Hu, HR Lan, D Huang, XM Li, KT ** - Frontiers in oncology, 2021 - frontiersin.org
Colorectal cancer (CRC) is the second leading cause of cancer death in the world.
Immunotherapy using monoclonal antibodies, immune-checkpoint inhibitors, adoptive cell …