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An improved yeast transformation method for the generation of very large human antibody libraries
Antibody library selection by yeast display technology is an efficient and highly sensitive
method to identify binders to target antigens. This powerful selection tool, however, is often …
method to identify binders to target antigens. This powerful selection tool, however, is often …
Cloning and characterization of a sialidase from the filamentous fungus, Aspergillus fumigatus
ML Warwas, JHF Yeung, D Indurugalla… - Glycoconjugate …, 2010 - Springer
A gene encoding a putative sialidase was identified in the genome of the opportunistic
fungal pathogen, Aspergillus fumigatus. Computational analysis showed that this protein …
fungal pathogen, Aspergillus fumigatus. Computational analysis showed that this protein …
Maximization of negative correlations in time-course gene expression data for enhancing understanding of molecular pathways
Positive correlation can be diversely instantiated as shifting, scaling or geometric pattern,
and it has been extensively explored for time-course gene expression data and pathway …
and it has been extensively explored for time-course gene expression data and pathway …
Correlating Gene Expression Variation with cis-Regulatory Polymorphism in Saccharomyces cerevisiae
Identifying the nucleotides that cause gene expression variation is a critical step in
dissecting the genetic basis of complex traits. Here, we focus on polymorphisms that are …
dissecting the genetic basis of complex traits. Here, we focus on polymorphisms that are …
Clustering of DNA words and biological function: a proof of principle
Relevant words in literary texts (key words) are known to be clustered, while common words
are randomly distributed. Given the clustered distribution of many functional genome …
are randomly distributed. Given the clustered distribution of many functional genome …
BayesPI-a new model to study protein-DNA interactions: a case study of condition-specific protein binding parameters for Yeast transcription factors
J Wang, Morigen - BMC bioinformatics, 2009 - Springer
Abstract Background We have incorporated Bayesian model regularization with biophysical
modeling of protein-DNA interactions, and of genome-wide nucleosome positioning to study …
modeling of protein-DNA interactions, and of genome-wide nucleosome positioning to study …
[HTML][HTML] Discovering sequences with potential regulatory characteristics
M Bina, P Wyss, SA Lazarus, SR Shah, W Ren… - Genomics, 2009 - Elsevier
We developed a computational model to explore the hypothesis that regulatory instructions
are context dependent and conveyed through specific 'codes' in human genomic DNA. We …
are context dependent and conveyed through specific 'codes' in human genomic DNA. We …
Investigating the sequence landscape in the Drosophila initiator core promoter element using an enhanced MARZ algorithm
The core promoter elements are important DNA sequences for the regulation of RNA
polymerase II transcription in eukaryotic cells. Despite the broad evolutionary conservation …
polymerase II transcription in eukaryotic cells. Despite the broad evolutionary conservation …
Methods for transforming yeast
US9200270B2 - Methods for transforming yeast - Google Patents US9200270B2 - Methods for
transforming yeast - Google Patents Methods for transforming yeast Download PDF Info …
transforming yeast - Google Patents Methods for transforming yeast Download PDF Info …
Common peptides shed light on evolution of Olfactory Receptors
Abstract Background Olfactory Receptors (ORs) form the largest multigene family in
vertebrates. Their evolution and their expansion in the vertebrate genomes was the subject …
vertebrates. Their evolution and their expansion in the vertebrate genomes was the subject …