Understanding the broad influence of sex hormones and sex differences in the brain

BS McEwen, TA Milner - Journal of neuroscience research, 2017 - Wiley Online Library
Sex hormones act throughout the entire brain of both males and females via both genomic
and nongenomic receptors. Sex hormones can act through many cellular and molecular …

Assessing rodent hippocampal involvement in the novel object recognition task. A review

SJ Cohen, RW Stackman Jr - Behavioural brain research, 2015 - Elsevier
The novel object recognition (NOR) task has emerged as a popular method for testing the
neurobiology of nonspatial memory in rodents. This task exploits the natural tendency of …

Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress

S Liang, T Wang, X Hu, J Luo, W Li, X Wu, Y Duan… - Neuroscience, 2015 - Elsevier
Increasing numbers of studies have suggested that the gut microbiota is involved in the
pathophysiology of stress-related disorders. Chronic stress can cause behavioral, cognitive …

Sex differences and the neurobiology of affective disorders

DR Rubinow, PJ Schmidt - Neuropsychopharmacology, 2019 - nature.com
Observations of the disproportionate incidence of depression in women compared with men
have long preceded the recent explosion of interest in sex differences. Nonetheless, the …

Sex differences in nucleus accumbens transcriptome profiles associated with susceptibility versus resilience to subchronic variable stress

GE Hodes, ML Pfau, I Purushothaman, HF Ahn… - Journal of …, 2015 - jneurosci.org
Depression and anxiety disorders are more prevalent in females, but the majority of
research in animal models, the first step in finding new treatments, has focused …

Physiology and neurobiology of stress and adaptation: central role of the brain

BS McEwen - Physiological reviews, 2007 - journals.physiology.org
The brain is the key organ of the response to stress because it determines what is
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …

Stress and the brain: from adaptation to disease

ER De Kloet, M Joëls, F Holsboer - Nature reviews neuroscience, 2005 - nature.com
In response to stress, the brain activates several neuropeptide-secreting systems. This
eventually leads to the release of adrenal corticosteroid hormones, which subsequently feed …

Sex in the brain: hormones and sex differences

J Marrocco, BS McEwen - Dialogues in clinical neuroscience, 2016 - Taylor & Francis
Contrary to popular belief, sex hormones act throughout the entire brain of both males and
females via both genomic and nongenomic receptors. Many neural and behavioral functions …

Neuromodulation of aerobic exercise—a review

S Heijnen, B Hommel, A Kibele, LS Colzato - Frontiers in psychology, 2016 - frontiersin.org
Running, and aerobic exercise in general, is a physical activity that increasingly many
people engage in but that also has become popular as a topic for scientific research. Here …

Neurobiology of resilience

SJ Russo, JW Murrough, MH Han, DS Charney… - Nature …, 2012 - nature.com
Humans exhibit a remarkable degree of resilience in the face of extreme stress, with most
resisting the development of neuropsychiatric disorders. Over the past 5 years, there has …