Nanomaterial-based contrast agents

JC Hsu, Z Tang, OE Eremina, AM Sofias… - Nature Reviews …, 2023 - nature.com
Medical imaging, which empowers the detection of physiological and pathological
processes within living subjects, has a vital role in both preclinical and clinical diagnostics …

Current capabilities and future perspectives of FCS: super-resolution microscopy, machine learning, and in vivo applications

J Sankaran, T Wohland - Communications Biology, 2023 - nature.com
Fluorescence correlation spectroscopy (FCS) is a single molecule sensitive tool for the
quantitative measurement of biomolecular dynamics and interactions. Improvements in …

Single-molecule FRET for probing nanoscale biomolecular dynamics

D Nettels, N Galvanetto, MT Ivanović, M Nüesch… - Nature Reviews …, 2024 - nature.com
Single-molecule spectroscopy is a powerful method for studying the physics of molecular
systems, particularly biomolecules, such as proteins and nucleic acids. By avoiding …

Molecular electronics sensors on a scalable semiconductor chip: A platform for single-molecule measurement of binding kinetics and enzyme activity

CW Fuller, PS Padayatti… - Proceedings of the …, 2022 - National Acad Sciences
For nearly 50 years, the vision of using single molecules in circuits has been seen as
providing the ultimate miniaturization of electronic chips. An advanced example of such a …

Mechanisms of Biomolecular Self‐Assembly Investigated Through In Situ Observations of Structures and Dynamics

SY Schmid, K Lachowski, HT Chiang… - Angewandte Chemie …, 2023 - Wiley Online Library
Biomolecular self‐assembly of hierarchical materials is a precise and adaptable bottom‐up
approach to synthesizing across scales with considerable energy, health, environment …

Monte Carlo samplers for efficient network inference

Z Kilic, M Schweiger, C Moyer… - PLoS computational …, 2023 - journals.plos.org
Accessing information on an underlying network driving a biological process often involves
interrupting the process and collecting snapshot data. When snapshot data are stochastic …

Single-molecule diffusometry reveals no catalysis-induced diffusion enhancement of alkaline phosphatase as proposed by FCS experiments

Z Chen, A Shaw, H Wilson… - Proceedings of the …, 2020 - National Acad Sciences
Theoretical and experimental observations that catalysis enhances the diffusion of enzymes
have generated exciting implications about nanoscale energy flow, molecular chemotaxis …

[HTML][HTML] Utilizing Molecular Dynamics Simulations, Machine Learning, Cryo-EM, and NMR Spectroscopy to Predict and Validate Protein Dynamics

A Son, W Kim, J Park, W Lee, Y Lee, S Choi… - International Journal of …, 2024 - mdpi.com
Protein dynamics play a crucial role in biological function, encompassing motions ranging
from atomic vibrations to large-scale conformational changes. Recent advancements in …

Fluorescence Microscopy: a statistics-optics perspective

M Fazel, KS Grussmayer, B Ferdman, A Radenovic… - Reviews of Modern …, 2024 - APS
Fundamental properties of light unavoidably impose features on images collected using
fluorescence microscopes. Accounting for these features is often critical in quantitatively …

Single particle level dynamics of photoactivation and suppression of Auger recombination in aqueous Cu-doped CdS quantum dots

S Das, G Rana, F Ali, A Datta - Nanoscale, 2023 - pubs.rsc.org
Cu-doped CdS quantum dots (QDs) have been synthesized in water using 3-
mercaptopropionic acid (3-MPA) as the cap** agent. They exhibit intense …