Immunotherapy is moving to the frontier of cancer treatment. Drug delivery systems (DDSs)
have greatly advanced the development of cancer immunotherapeutic regimen and …

Immune system evasion by cancer cells is one of the hallmarks of cancers, and it occurs with
the support of tumor-associated immune cells (TICs) in the tumor microenvironment that …

Nowadays, a potent challenge in cancer treatment is considered the lack of efficacious
strategy, which has not been able to significantly reduce mortality. Chemoimmunotherapy …

Background In breast cancer (BC), tumor‐associated macrophages (TAMs) are an important
component of the tumor microenvironment and are closely related to poor prognosis. A …

The rising demand for chitosan is propelled by its diverse functional properties, including
biocompatibility, biodegradability, antimicrobial activity, and non-toxic nature. Its widespread …

Breast cancer characterized as “cold tumors” exhibit low levels of immune cell infiltration,
which limits the efficacy of conventional immunotherapy. Recent studies have focused on …

PLGA was functionalized with PEG and biotin using click chemistry to generate a biotin
receptor targeted copolymer (biotinylated–PEG-PLGA) which in turn was used to fabricate …

Most of the current antitumor therapeutics were developed targeting the cancer cells only.
Unfortunately, in the majority of tumors, this single-dimensional therapy is found to be …

There are always some components in the tumor microenvironment (TME), such as tumor-
associated macrophages (TAMs), that help tumor cells escape the body's immune …

The kind of environment that is present around the tumor is called the tumor
microenvironment (TME). Various factors responsible for develo** the TME are hypoxia …