Zebrafish as an emerging model for dyslipidemia and associated diseases

J Ka, SW ** - Journal of Lipid and Atherosclerosis, 2020 - pmc.ncbi.nlm.nih.gov
Dyslipidemia related diseases such as hyperlipidemia and atherosclerosis are the leading
cause of death in humans. While cellular and molecular basis on the pathophysiology of …

The zebrafish model system for dyslipidemia and atherosclerosis research: Focus on environmental/exposome factors and genetic mechanisms

M Vasyutina, A Alieva, O Reutova, V Bakaleiko… - Metabolism, 2022 - Elsevier
Dyslipidemias and atherosclerosis play a pivotal role in cardiovascular risk and disease.
Although some pathophysiological mechanisms underlying these conditions have been …

Genome-wide association study of metabolic syndrome in Korean populations

SW Oh, JE Lee, E Shin, H Kwon, EK Choe, SY Choi… - PloS one, 2020 - journals.plos.org
Metabolic syndrome (MetS) which is caused by obesity and insulin resistance, is well known
for its predictive capability for the risk of type 2 diabetes mellitus and cardiovascular disease …

[HTML][HTML] From mother to child: epigenetic signatures of hyperglycemia and obesity during pregnancy

M Franzago, P Borrelli, M Di Nicola, P Cavallo… - Nutrients, 2024 - mdpi.com
Background: In utero exposure to maternal hyperglycemia and obesity can trigger
detrimental effects in the newborn through epigenetic programming. We aimed to assess the …

The association of type 2 diabetes loci identified in genome-wide association studies with metabolic syndrome and its components in a Chinese population with type 2 …

X Kong, X Zhang, X **ng, B Zhang, J Hong, W Yang - PloS one, 2015 - journals.plos.org
Metabolic syndrome (MetS) is prevalent in type 2 diabetes (T2D) patients. The comorbidity of
MetS and T2D increases the risk of cardiovascular complications. The aim of the present …

Longitudinal analysis is more powerful than cross-sectional analysis in detecting genetic association with neuroimaging phenotypes

Z Xu, X Shen, W Pan… - PloS one, 2014 - journals.plos.org
Most existing genome-wide association analyses are cross-sectional, utilizing only
phenotypic data at a single time point, eg baseline. On the other hand, longitudinal studies …

Antioxidant minerals modified the association between iron and type 2 diabetes in a Chinese population

T Xu, S Wan, J Shi, T Xu, L Wang, Y Guan, J Luo, Y Luo… - Nutrients, 2024 - mdpi.com
Inconsistent findings exist regarding the relationship between heme iron intake and type 2
diabetes (T2D) among Western and Eastern populations. Easterners tend to consume a …

Nutrigenetic variants and response to diet/lifestyle intervention in obese subjects: A pilot study

M Franzago, M Di Nicola, F Fraticelli, M Marchioni… - Acta Diabetologica, 2022 - Springer
Aims Nutritional and lifestyle interventions can contribute to prevent and treat obesity and its
complications; however, genetic background may influence the success of a therapy. The …

The high prevalence of low HDL-cholesterol levels and dyslipidemia in rural populations in Northwestern China

P Ge, C Dong, X Ren, E Weiderpass, C Zhang, H Fan… - PloS one, 2015 - journals.plos.org
Background Dyslipidemia is a major health problem in China and an important modifiable
cardiovascular disease (CVD) risk factor. This study aimed to describe the prevalence of …

Associations between serum hepcidin, ferritin and Hb concentrations and type 2 diabetes risks in a Han Chinese population

X Guo, D Zhou, P An, Q Wu, H Wang, A Wu… - British journal of …, 2013 - cambridge.org
Systemic Fe overload can contribute to abnormal glucose metabolism and the onset of type
2 diabetes (T2D). Although hepcidin is the master regulator of systemic Fe homeostasis, few …