Radiation therapy plays an integral role in the management of head and neck cancers
(HNCs). While most HNC patients have historically been treated with photon-based …

Abstract 4D multi-image-based (4D MIB) optimization is a form of robust optimization where
different uncertainty scenarios, due to anatomy variations, are considered via multiple image …

Purpose We hypothesized that patients with oropharyngeal cancer treated with intensity
modulated proton therapy (IMPT) would have lower symptom burdens, as measured by …

Purpose Reirradiation of head and neck (H&N) cancer is a clinical challenge. Proton
radiation therapy (PRT) offers dosimetric advantages for normal tissue sparing and may …

Background We report the first clinical experience and toxicity of multifield optimization
(MFO) intensity modulated proton therapy (IMPT) for patients with head and neck tumors …

Purpose A single-institution prospective study was conducted to assess disease control and
toxicity of proton therapy for patients with head and neck cancer. Methods and Materials …

Background Accurate and efficient dose calculation is essential for on‐line adaptive
planning in proton therapy. Deep learning (DL) has shown promising dose prediction results …

Purpose We propose linear energy transfer (LET)-guided robust optimization in intensity
modulated proton therapy for head and neck cancer. This method simultaneously considers …

Purpose To investigate how spot size and spacing affect plan quality, robustness, and
interplay effects of robustly optimized intensity modulated proton therapy (IMPT) for lung …

Abstract Background and Purpose In this multicentric in silico trial we compared photon,
proton, and carbon-ion radiotherapy plans for re-irradiation of patients with squamous cell …