B and T lymphocytes are the mediators of immunity, but their function is under the control of
dendritic cells. Dendritic cells in the periphery capture and process antigens, express …

Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells …

During the last five years, the development of bioinformatics and EST databases has been
primarily responsible for the identification of many new chemokines and chemokine …

Defensins contribute to host defense by disrupting the cytoplasmic membrane of
microorganisms. This report shows that human β-defensins are also chemotactic for …

Interleukin 17–producing T helper cells (T H-17 cells) are important in experimental
autoimmune encephalomyelitis, but their route of entry into the central nervous system …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

It is now possible to grow DC-like cells in culture17-21 and extensive cell membrane
processes that are acquired late the first monoclonal antibodies (MoAbs) 22, 23 that react …

DCs (dendritic cells) function as sentinels of the immune system. They traffic from the blood
to the tissues where, while immature, they capture antigens. They then leave the tissues and …

Chemokine receptor CCR6 is expressed on various cells such as B cells, immature dendritic
cells, innate lymphoid cells (ILCs), regulatory CD4 T cells, and Th17 cells. CCL20 is the only …

The immune system generally avoids horror autotoxicus or autoimmunity, an attack against
the body's own constituents. This avoidance requires that self-reactive T cells be actively …