The neurotransmitter serotonin is an evolutionary ancient molecule that has remarkable
modulatory effects in almost all central nervous system integrative functions, such as mood …

Genetic factors contribute to the phenotype of drug response. We systematically analyzed all
available pharmacogenetic data from Medline databases (1970–2003) on the impact that …

Bipolar disorder (also known as manic depressive illness) is a complex genetic disorder in
which the core feature is pathological disturbance in mood (affect) ranging from extreme …

Abstract The serotonin transporter (5-HTT) gene is a promising candidate for introducing the
heritability of interindividual variation in personality and the genetic susceptibility for various …

In the last decade the serotonin transporter gene promoter polymorphism (5-HTTLPR) was
likely the most studied genetic variant as predictor of antidepressant response. Nevertheless …

Major Depressive Disorder (MDD) is a highly prevalent psychiatric disorder worldwide. It
causes individual suffering, loss of productivity, increased health care costs and high suicide …

Depression is one of the most common psychiatric disorders worldwide, affecting
approximately 280 million people, with probably much higher unrecorded cases …

This systematic review summarizes pharmacogenetic studies on antidepressant response
and side effects. Out of the 17 genes we reviewed, 8 genes were entered into the meta …

The genetic basis of major depressive disorder (MDD) has been investigated extensively,
but the identification of MDD genes has been hampered by conflicting results from …

The serotonin transporter gene promoter polymorphism (5-HTTLPR) has been repeatedly
associated with antidepressant response in mood disorder patients, but findings are not …