Tissue homeostasis is regulated by apoptosis, the cell-suicide programme that is executed
by proteases called caspases. The Bcl2 family of intracellular proteins is the central …

The major challenge in treating cancer is that many tumor cells carry mutations in key
apoptotic genes such as p53, Bcl family proteins or those affecting caspase signaling. Such …

Wie kommunizieren Zellen? Was steuert die Aktivität von Zellen oder Enzymen? Wie verläuft
die Enstehung einer Krebszelle? Diese und ähnliche Fragen sind zentraler Gegenstand der …

The conversion of muscle into meat is a complex process in which all mechanisms
responsible for the development of meat qualities are very likely interdependent. Colour and …

The human genomic sequencing effort has revealed the presence of a large number of Rho
GTPases encoded by the human genome. Here we report the characterization of a new …

Controversy has surrounded a role for apoptosis in the loss of neurons in Parkinson's
disease (PD). Although a variety of evidence has supported an apoptotic contribution to PD …

Phytochemicals are recognized as playing an important role in cancer prevention by fruits
and vegetables. The avocado is a widely grown and consumed fruit that is high in nutrients …

The serine/threonine kinase Akt/protein kinase B inhibits apoptosis induced by a variety of
stimuli, including overexpression or activation of proapoptotic Bcl-2 family members. The …

Meat tenderisation is majoritarily enzymatic in nature and involves endogenous proteolytic
systems. Up to date, scientists have focused their attention on two systems, ie the cathepsins …

Mitochondria play a crucial role in cellular homeostasis, which justifies the increasing
interest in map** the different components of these organelles. Here we have focused our …