Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature
Clinicopathologic correlation studies are critically important for the field of Alzheimer disease
(AD) research. Studies on human subjects with autopsy confirmation entail numerous …
(AD) research. Studies on human subjects with autopsy confirmation entail numerous …
Mild cognitive impairment
Mild cognitive impairment is a syndrome defined as cognitive decline greater than expected
for an individual's age and education level but that does not interfere notably with activities …
for an individual's age and education level but that does not interfere notably with activities …
An active and socially integrated lifestyle in late life might protect against dementia
L Fratiglioni, S Paillard-Borg, B Winblad - The Lancet Neurology, 2004 - thelancet.com
The recent availability of longitudinal data on the possible association of different lifestyles
with dementia and Alzheimer's disease (AD) allow some preliminary conclusions on this …
with dementia and Alzheimer's disease (AD) allow some preliminary conclusions on this …
The cognitive neuroscience of ageing
C Grady - Nature Reviews Neuroscience, 2012 - nature.com
The availability of neuroimaging technology has spurred a marked increase in the human
cognitive neuroscience literature, including the study of cognitive ageing. Although there is a …
cognitive neuroscience literature, including the study of cognitive ageing. Although there is a …
Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention
C Qiu, M Kivipelto, E Von Strauss - Dialogues in clinical …, 2009 - Taylor & Francis
More than 25 million people in the world today are affected by dementia, most suffering from
Alzheimer's disease. In both developed and develo** nations, Alzheimer's disease has …
Alzheimer's disease. In both developed and develo** nations, Alzheimer's disease has …
Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models
The goal of this review is to discuss how behavioral tests in mice relate to the pathological
and neuropsychological features seen in human Alzheimer's disease (AD), and present a …
and neuropsychological features seen in human Alzheimer's disease (AD), and present a …
Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen project
HX Wang, A Karp, B Winblad… - American journal of …, 2002 - academic.oup.com
Recent findings suggest that a rich social network may decrease the risk of develo**
dementia. The authors hypothesized that such a protective effect may be due to social …
dementia. The authors hypothesized that such a protective effect may be due to social …
Natural history of mild cognitive impairment in older persons
DA Bennett, RS Wilson, JA Schneider, DA Evans… - Neurology, 2002 - AAN Enterprises
Background: Cognitive abilities of older persons range from normal, to mild cognitive
impairment, to dementia. Few large longitudinal studies have compared the natural history …
impairment, to dementia. Few large longitudinal studies have compared the natural history …
The neuropsychological profile of Alzheimer disease
S Weintraub, AH Wicklund… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Neuropsychological assessment has featured prominently over the past 30 years in the
characterization of dementia associated with Alzheimer disease (AD). Clinical …
characterization of dementia associated with Alzheimer disease (AD). Clinical …
Prodromal Alzheimer's disease: successive emergence of the clinical symptoms
H Amieva, M Le Goff, X Millet… - Annals of Neurology …, 2008 - Wiley Online Library
Objective Whereas cognitive deficits are known to be detectable long before the typical
symptoms of Alzheimer's disease (AD) are evident, previous studies have failed to …
symptoms of Alzheimer's disease (AD) are evident, previous studies have failed to …