Over more than 30 years in vivo MR spectroscopic imaging (MRSI) has undergone an
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …

Magnetic resonance spectroscopic imaging (MRSI) offers considerable promise for
monitoring metabolic alterations associated with disease or injury; however, to date, these …

Spectral editing in in vivo 1H‐MRS provides an effective means to measure low‐
concentration metabolite signals that cannot be reliably measured by conventional MRS …

Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …

Abstract Magnetic Resonance Spectroscopy (MRS) allows for a non-invasive and non-
ionizing determination of in vivo tissue concentrations and metabolic turn-over rates of more …

Objectives Available clinical magnetic resonance spectroscopic imaging (MRSI) sequences
are hampered by long scan times, low spatial resolution, strong field inhomogeneities …

Objectives Noninvasive, affordable, and reliable map** of brain glucose metabolism is of
critical interest for clinical research and routine application as metabolic impairment is linked …

Importance: Gliomas, tumors of the central nervous system, are classically diagnosed
through invasive surgical biopsy and subsequent histopathological study. Innovations in …

Objective To summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and to highlight the latest bench-to-bedside developments. Methods …

Objectives Successful neurosurgical intervention in gliomas depends on the precision of the
preoperative definition of the tumor and its margins since a safe maximum resection …