Measuring high-altitude adaptation

LG Moore - Journal of applied physiology, 2017 - journals.physiology.org
High altitudes (> 8,000 ft or 2,500 m) provide an experiment of nature for measuring
adaptation and the physiological processes involved. Studies conducted over the past~ 25 …

Hypoxia-induced oxidative stress modulation with physical activity

T Debevec, GP Millet, V Pialoux - Frontiers in physiology, 2017 - frontiersin.org
Increased oxidative stress, defined as an imbalance between prooxidants and antioxidants,
resulting in molecular damage and disruption of redox signaling, is associated with …

Technical recommendations for the use of carotid duplex ultrasound for the assessment of extracranial blood flow

KN Thomas, NCS Lewis, BG Hill… - American Journal of …, 2015 - journals.physiology.org
Duplex ultrasound is an evolving technology that allows the assessment of volumetric blood
flow in the carotid and vertebral arteries during a range of interventions along the spectrum …

Humans in hypoxia: a conspiracy of maladaptation?!

JA Dempsey, BJ Morgan - Physiology, 2015 - journals.physiology.org
We address adaptive vs. maladaptive responses to hypoxemia in healthy humans and
hypoxic-tolerant species during wakefulness, sleep, and exercise. Types of hypoxemia …

Hematocrit, hemoglobin and red blood cells are associated with vascular function and vascular structure in men

S Kishimoto, T Maruhashi, M Kajikawa, S Matsui… - Scientific reports, 2020 - nature.com
High and low hematocrit (Hct) and hemoglobin (Hb) levels are associated with the risk of
cardiovascular disease. The purpose of this study was to determine the relationships of Hct …

Recent insights into mechanisms of hypoxia‐induced vasodilatation in the human brain

JMJR Carr, RL Hoiland, IA Fernandes… - The Journal of …, 2024 - Wiley Online Library
The cerebral vasculature manages oxygen delivery by adjusting arterial blood in‐flow in the
face of reductions in oxygen availability. Hypoxic cerebral vasodilatation, and the associated …

Blood pressure at high altitude: physiology and clinical implications

G Bilo, S Caravita, C Torlasco… - Polish Heart Journal …, 2019 - journals.viamedica.pl
High altitude is a fascinating model of hypoxia effects on the human body but is also an
extreme environment which directly influences millions of people who either travel to high …

Impact of extreme exercise at high altitude on oxidative stress in humans

J Quindry, C Dumke, D Slivka… - The Journal of …, 2016 - Wiley Online Library
Exercise and oxidative stress research continues to grow as a physiological subdiscipline.
The influence of high altitude on exercise and oxidative stress is among the recent topics of …

Systemic hypertension at high altitude

O Narvaez-Guerra, K Herrera-Enriquez… - …, 2018 - ahajournals.org
568 Hypertension September 2018 prevalence of hypertension with a 2% increase for
every≈ 100 m (≈ 330 ft)-increase in altitude above 3000 mASL (≈ 9800 ft). 16 …

End tidal-to-arterial CO2 and O2 gas gradients at low- and high-altitude during dynamic end-tidal forcing

MM Tymko, PN Ainslie, DB MacLeod… - American Journal …, 2015 - journals.physiology.org
We sought to characterize and quantify the performance of a portable dynamic end-tidal
forcing (DEF) system in controlling the partial pressure of arterial CO2 (PaCO2) and O2 …