Mitochondria are highly dynamic organelles that constantly undergo fission and fusion.
Disruption of mitochondrial dynamics undermines their function and causes several human …

Cell–cell fusion remains the least understood type of membrane fusion process. However,
the last few years have brought about major advances in understanding fusion between …

The endoplasmic reticulum (ER) network consists of tubules with high membrane curvature
in cross-section, generated by the reticulons and REEPs. These proteins have two pairs of …

Dynamin superfamily proteins (DSPs) mediate membrane fission and fusion necessary for
endocytosis, organelle biogenesis and maintenance, as well as for bacterial cytokinesis …

Myomerger is a muscle-specific membrane protein involved in formation of multinucleated
muscle cells by mediating the transition from the early hemifusion stage to complete fusion …

Organelles display characteristic morphologies that are intimately tied to their cellular
function, but how organelles are shaped is poorly understood. The endoplasmic reticulum is …

Dynamin superfamily proteins are multidomain mechano‐chemical GTPases which are
implicated in nucleotide‐dependent membrane remodeling events. A prominent feature of …

Flaviviruses, including dengue virus and Zika virus, extensively remodel the cellular
endomembrane network to generate replication organelles that promote viral genome …

Homotypic membrane fusion catalyzed by the atlastin (ATL) GTPase sustains the branched
endoplasmic reticulum (ER) network in metazoans. Our recent discovery that two of the three …

Endoplasmic reticulum (ER) membrane junctions are formed by the dynamin-like GTPase
atlastin (ATL). Deletion of ATL results in long unbranched ER tubules in cells, and mutation …