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Regulation of microRNA biogenesis
M Ha, VN Kim - Nature reviews Molecular cell biology, 2014 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …
[HTML][HTML] Cytoplasmic RNA decay pathways-Enzymes and mechanisms
RNA decay plays a crucial role in post-transcriptional regulation of gene expression. Work
conducted over the last decades has defined the major mRNA decay pathways, as well as …
conducted over the last decades has defined the major mRNA decay pathways, as well as …
To kill a microRNA: emerging concepts in target-directed microRNA degradation
Abstract MicroRNAs (miRNAs) guide Argonaute (AGO) proteins to bind mRNA targets.
Although most targets are destabilized by miRNA–AGO binding, some targets induce …
Although most targets are destabilized by miRNA–AGO binding, some targets induce …
A guide to miRNAs in inflammation and innate immune responses
C Nejad, HJ Stunden, MP Gantier - The FEBS journal, 2018 - Wiley Online Library
The discovery of micro RNA s (miRNAs) in the early 1990's has revolutionized our thinking
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …
Dysregulation of microRNA biogenesis and gene silencing in cancer
MicroRNAs (miRNAs) are small noncoding RNAs that suppress the abundance of partially
complementary mRNAs and inhibit their translation. Each miRNA can regulate hundreds of …
complementary mRNAs and inhibit their translation. Each miRNA can regulate hundreds of …
MicroRNA turnover: when, how, and why
S Rüegger, H Großhans - Trends in biochemical sciences, 2012 - cell.com
MicroRNAs (miRNAs) are short (∼ 22 nucleotide) RNAs that are important for the regulation
of numerous biological processes. Accordingly, the expression of miRNAs is itself tightly …
of numerous biological processes. Accordingly, the expression of miRNAs is itself tightly …
The biogenesis and regulation of animal microRNAs
H Kim, YY Lee, VN Kim - Nature Reviews Molecular Cell Biology, 2024 - nature.com
MicroRNAs (miRNAs) are small, yet profoundly influential, non-coding RNAs that base-pair
with mRNAs to induce RNA silencing. Although the basic principles of miRNA biogenesis …
with mRNAs to induce RNA silencing. Although the basic principles of miRNA biogenesis …
Human mitochondrial RNA decay mediated by PNPase–hSuv3 complex takes place in distinct foci
RNA decay is usually mediated by protein complexes and can occur in specific foci such as
P-bodies in the cytoplasm of eukaryotes. In human mitochondria nothing is known about the …
P-bodies in the cytoplasm of eukaryotes. In human mitochondria nothing is known about the …
LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and promotes polyadenylation in human mitochondria
In human mitochondria, 10 mRNAs species are generated from a long polycistronic
precursor that is transcribed from the heavy chain of mitochondrial DNA, in theory yielding …
precursor that is transcribed from the heavy chain of mitochondrial DNA, in theory yielding …
MicroRNA degradation and turnover: regulating the regulators
Z Zhang, YW Qin, G Brewer… - Wiley Interdisciplinary …, 2012 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous, small noncoding RNAs that play important
regulatory roles in gene expression. The control of miRNA biogenesis has been well …
regulatory roles in gene expression. The control of miRNA biogenesis has been well …