[HTML][HTML] Diagnostic modalities of non-alcoholic fatty liver disease: from biochemical biomarkers to multi-omics non-invasive approaches

E Martinou, M Pericleous, I Stefanova, V Kaur… - Diagnostics, 2022 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …

Using adipose‐derived mesenchymal stem cells to fight the metabolic complications of obesity: Where do we stand?

A Mikłosz, BE Nikitiuk, A Chabowski - Obesity Reviews, 2022 - Wiley Online Library
Obesity is a critical risk factor for the development of metabolic diseases, and its prevalence
is increasing worldwide. Stem cell‐based therapies have become a promising tool for …

Circulating fatty acids and risk of hepatocellular carcinoma and chronic liver disease mortality in the UK Biobank

Z Liu, H Huang, J **e, Y Xu, C Xu - Nature Communications, 2024 - nature.com
Nuclear magnetic resonance (NMR)-based plasma fatty acids are objective biomarkers of
many diseases. Herein, we aim to explore the associations of NMR-based plasma fatty acids …

Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease

G Xu, S Quan, J Schell, Y Gao, M Varmazyad… - Science …, 2024 - science.org
Acetyl-CoA synthetase short-chain family member 1 (ACSS1) uses acetate to generate
mitochondrial acetyl-CoA and is regulated by deacetylation by sirtuin 3. We generated an …

Bacteroides thetaiotaomicron ameliorates mouse hepatic steatosis through regulating gut microbial composition, gut-liver folate and unsaturated fatty acids …

H Li, XK Wang, M Tang, L Lei, JR Li, H Sun, J Jiang… - Gut …, 2024 - Taylor & Francis
Gut microbiota plays an essential role in the progression of nonalcoholic fatty liver disease
(NAFLD), making the gut-liver axis a potential therapeutic strategy. Bacteroides genus, the …

Precision medicine in fatty liver disease/non-alcoholic fatty liver disease

L Valenzuela-Vallejo, D Sanoudou… - Journal of Personalized …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, and is
related to fatal and non-fatal liver, metabolic, and cardiovascular complications. Its non …

Single‐cell transcriptomics stratifies organoid models of metabolic dysfunction‐associated steatotic liver disease

A Hess, SD Gentile, A Ben Saad, RU Rahman… - The EMBO …, 2023 - embopress.org
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a growing cause of
morbidity with limited treatment options. Thus, accurate in vitro systems to test new therapies …

[HTML][HTML] Alteration of fecal microbiome and metabolome by mung bean coat improves diet-induced non-alcoholic fatty liver disease in mice

D Hou, J Tang, M Huan, F Liu, S Zhou… - Food Science and Human …, 2022 - Elsevier
Dysbiosis of gut microbiota and its derived metabolites has been linked to the occurrence
and development of nonalcoholic fatty liver disease. Our previous study has demonstrated …

Red rice bran extract alleviates high-fat diet-induced non-alcoholic fatty liver disease and dyslipidemia in mice

N Munkong, S Somnuk, N Jantarach, K Ruxsanawet… - Nutrients, 2023 - mdpi.com
Red rice bran extract (RRBE) is rich in phytonutrients and has been shown to have anti-
diabetic, anti-inflammatory, and antioxidant properties. However, its anti-hepatic steatosis …

Hepatic and serum branched‐chain fatty acid profile in patients with nonalcoholic fatty liver disease: A case–control study

JI Martínez‐Montoro, MÁ Núñez‐Sánchez… - …, 2023 - Wiley Online Library
Objective Alterations in the hepatic lipidome are a crucial factor involved in the
pathophysiology of nonalcoholic fatty liver disease (NAFLD). The aim of this study was to …