Bioinspired polymer vesicles and membranes for biological and medical applications

CG Palivan, R Goers, A Najer, X Zhang, A Car… - Chemical society …, 2016‏ - pubs.rsc.org
Biological membranes play an essential role in living organisms by providing stable and
functional compartments, preserving cell architecture, whilst supporting signalling and …

All wrapped up: stabilization of enzymes within single enzyme nanoparticles

R Chapman, MH Stenzel - Journal of the American Chemical …, 2019‏ - ACS Publications
Enzymes are extremely useful in many industrial and pharmaceutical areas due to their
ability to catalyze reactions with high selectivity. In order to extend their lifetime, significant …

Polymeric vesicles: from drug carriers to nanoreactors and artificial organelles

P Tanner, P Baumann, R Enea, O Onaca… - Accounts of chemical …, 2011‏ - ACS Publications
One strategy in modern medicine is the development of new platforms that combine
multifunctional compounds with stable, safe carriers in patient-oriented therapeutic …

Compartmentalization approaches in soft matter science: from nanoreactor development to organelle mimics

L Schoonen, JCM Van Hest - Advanced Materials, 2016‏ - Wiley Online Library
Compartmentalization is an essential feature found in living cells to ensure that biological
processes occur without being affected by undesired external influences. Over the years …

Stimuli‐responsive polymersomes as nanocarriers for drug and gene delivery

O Onaca, R Enea, DW Hughes… - Macromolecular …, 2009‏ - Wiley Online Library
Polymeric formulations (micelles, vesicles etc.) have emerged as versatile drug carriers due
to their increased stability, site specificity, blood circulation resistance and thus overall …

[PDF][PDF] Positional assembly of enzymes in polymersome nanoreactors for cascade reactions

DM Vriezema, PML Garcia, N Sancho Oltra… - Angewandte Chemie …, 2007‏ - academia.edu
The cellular environment can be regarded as a highly complex synthetic medium, in which
numerous multistep reactions take place simultaneously with unsurpassed efficiency and …

Cyclopentyl methyl ether (CPME): a versatile eco‐friendly solvent for applications in biotechnology and biorefineries

G de Gonzalo, AR Alcántara… - …, 2019‏ - Wiley Online Library
The quest for sustainable solvents is currently a matter of intense research and
development, as solvents significantly contribute heavily to the waste generated by chemical …

A three‐enzyme cascade reaction through positional assembly of enzymes in a polymersome nanoreactor

SFM Van Dongen, M Nallani… - … A European Journal, 2009‏ - Wiley Online Library
Porous polymersomes based on block copolymers of isocyanopeptides and styrene have
been used to anchor enzymes at three different locations, namely, in their lumen (glucose …

Biohybrid polymer capsules

SFM van Dongen, HPM de Hoog, RJRW Peters… - Chemical …, 2009‏ - ACS Publications
Compartmentalization is one of the most powerful tools in nature's arsenal to structure
metabolic and signaling pathways. Many of the catalytic reactions taking place in cells …

Selective and responsive nanoreactors

K Renggli, P Baumann, K Langowska… - Advanced Functional …, 2011‏ - Wiley Online Library
Chemical reactions can be confined to nanoscale compartments by encapsulating catalysts
in hollow nanoobjects. Such reaction compartments effectively become nanoreactors when …