Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …
Biomimetic antimicrobial polymers: Recent advances in molecular design
The increasing prevalence of antibiotic-resistant bacterial infections, coupled with the
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …
Helical polymers for biological and medical applications
T Leigh, P Fernandez-Trillo - Nature Reviews Chemistry, 2020 - nature.com
Helices are the most prevalent secondary structure in biomolecules and play vital roles in
their activity. Chemists have been fascinated with mimicking this molecular conformation …
their activity. Chemists have been fascinated with mimicking this molecular conformation …
Antimicrobial susceptibility testing of antimicrobial peptides to better predict efficacy
During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …
Photo‐Enhanced Antimicrobial Activity of Polymers Containing an Embedded Photosensitiser
This work presents the synthesis of a novel photosensitive acrylate monomer for use as both
a self‐catalyst in the photoinduced electron/energy transfer–reversible addition …
a self‐catalyst in the photoinduced electron/energy transfer–reversible addition …
Host defense peptide mimicking poly-β-peptides with fast, potent and broad spectrum antibacterial activities
Microbial infections have always been serious challenges to human health considering that
antibiotics almost inevitably induce microbial resistance. Therefore, it is urgent to develop a …
antibiotics almost inevitably induce microbial resistance. Therefore, it is urgent to develop a …
Sequence control as a powerful tool for improving the selectivity of antimicrobial polymers
Antimicrobial polymers appear as a promising alternative to tackle the current development
of bacterial resistance against conventional antibiotics as they rely on bacterial membrane …
of bacterial resistance against conventional antibiotics as they rely on bacterial membrane …
Synthetic star nanoengineered antimicrobial polymers as antibiofilm agents: Bacterial membrane disruption and cell aggregation
Antimicrobial resistance has become a worldwide issue, with multiresistant bacterial strains
emerging at an alarming rate. Multivalent antimicrobial polymer architectures such as bottle …
emerging at an alarming rate. Multivalent antimicrobial polymer architectures such as bottle …
Facial amphiphilicity-induced polymer nanostructures for antimicrobial applications
New antimicrobial agents are needed to address ever-increasing antimicrobial resistance
and a growing epidemic of infections caused by multidrug resistant pathogens. We design …
and a growing epidemic of infections caused by multidrug resistant pathogens. We design …
Impact of multivalence and self-assembly in the design of polymeric antimicrobial peptide mimics
Antimicrobial resistance is an increasingly serious challenge for public health and could
result in dramatic negative consequences for the health care sector during the next decades …
result in dramatic negative consequences for the health care sector during the next decades …