Advances in lithographic techniques for precision nanostructure fabrication in biomedical applications

K Stokes, K Clark, D Odetade, M Hardy… - Discover Nano, 2023 - Springer
Nano-fabrication techniques have demonstrated their vital importance in technological
innovation. However, low-throughput, high-cost and intrinsic resolution limits pose …

Diagnostic, therapeutic, and theranostic multifunctional microneedles

YN Ertas, D Ertas, A Erdem, F Segujja, S Dulchavsky… - Small, 2024 - Wiley Online Library
Microneedles (MNs) have maintained their popularity in therapeutic and diagnostic medical
applications throughout the past decade. MNs are originally designed to gently puncture the …

Swellable colorimetric microneedles for glucose detection based on glucose oxidase-like gold nanoparticles

X Li, J Lv, J Zhao, G Ling, P Zhang - Analytica Chimica Acta, 2024 - Elsevier
Background Regular blood glucose monitoring is very important for diabetic patients. The
composition of skin interstitial fluid (ISF) is similar to that of blood, which can be used for …

[HTML][HTML] Microneedle-based interstitial fluid extraction for drug analysis: Advances, challenges, and prospects

S Ma, J Li, L Pei, N Feng, Y Zhang - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Similar to blood, interstitial fluid (ISF) contains exogenous drugs and biomarkers and may
therefore substitute blood in drug analysis. However, current ISF extraction techniques …

3D‐Printed Hollow Microneedle‐Lateral Flow Devices for Rapid Blood‐Free Detection of C‐Reactive Protein and Procalcitonin

JG Turner, E Lay, U Jungwirth… - Advanced Materials …, 2023 - Wiley Online Library
Hollow microneedle devices as a technology for interstitial fluid extraction show promise for
the minimally invasive point‐of‐care detection of analytes. Despite increasing efforts toward …

Advances in biomedical systems based on microneedles: design, fabrication, and application

X Wang, Z Wang, M **ao, Z Li, Z Zhu - Biomaterials Science, 2024 - pubs.rsc.org
Wearable devices have become prevalent in biomedical studies due to their convenient
portability and potential utility in biomarker monitoring for healthcare. Accessing interstitial …

Polymeric Microneedles for Health Care Monitoring: An Emerging Trend

RL Pereira, KB Vinayakumar, S Sillankorva - ACS sensors, 2024 - ACS Publications
Bioanalyte collection by blood draw is a painful process, prone to needle phobia and
injuries. Microneedles can be engineered to penetrate the epidermal skin barrier and collect …

Microneedle-integrated sensors for extraction of skin interstitial fluid and metabolic analysis

J Yang, R Luo, L Yang, X Wang, Y Huang - International Journal of …, 2023 - mdpi.com
Skin interstitial fluid (ISF) has emerged as a fungible biofluid sample for blood serum and
plasma for disease diagnosis and therapy. The sampling of skin ISF is highly desirable …

Non-invasive glucose prediction and classification using NIR technology with machine learning

M Naresh, VS Nagaraju, S Kollem, J Kumar… - Heliyon, 2024 - cell.com
In this paper, a dual wavelength short near-infrared system is described for the detection of
glucose levels. The system aims to improve the accuracy of blood glucose detection in a …

Microneedles based on a biodegradable polymer—hyaluronic acid

J Chudzińska, A Wawrzyńczak, A Feliczak-Guzik - Polymers, 2024 - mdpi.com
Transdermal transport can be challenging due to the difficulty in diffusing active substances
through the outermost layer of the epidermis, as the primary function of the skin is to protect …