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[HTML][HTML] Diagnostic and prognostic biomarkers in renal clear cell carcinoma
Renal clear cell carcinoma (ccRCC) comprises over 75% of all renal tumors and arises in
the epithelial cells of the proximal convoluted tubule. Molecularly ccRCC is characterized by …
the epithelial cells of the proximal convoluted tubule. Molecularly ccRCC is characterized by …
Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease pathology
Recent advances in the understanding of basic pathological mechanisms in various
neurological diseases depend directly on the development of novel bioanalytical …
neurological diseases depend directly on the development of novel bioanalytical …
High‐resolution MALDI‐FT‐ICR MS imaging for the analysis of metabolites from formalin‐fixed, paraffin‐embedded clinical tissue samples
We present the first analytical approach to demonstrate the in situ imaging of metabolites
from formalin‐fixed, paraffin‐embedded (FFPE) human tissue samples. Using high …
from formalin‐fixed, paraffin‐embedded (FFPE) human tissue samples. Using high …
Spatial multiomics of lipids, N-glycans, and tryptic peptides on a single FFPE tissue section
Mass spectrometry imaging (MSI) is an emerging technology that is capable of map**
various biomolecules within their native spatial context, and performing spatial multiomics …
various biomolecules within their native spatial context, and performing spatial multiomics …
Sample preparation of formalin-fixed paraffin-embedded tissue sections for MALDI-mass spectrometry imaging
J Hermann, H Noels, W Theelen, M Lellig… - Analytical and …, 2020 - Springer
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MALDI
MSI) has become a powerful tool with a high potential relevance for the analysis of …
MSI) has become a powerful tool with a high potential relevance for the analysis of …
Mass spectrometry imaging, laser capture microdissection, and LC-MS/MS of the same tissue section
M Dilillo, D Pellegrini, R Ait-Belkacem… - Journal of proteome …, 2017 - ACS Publications
Mass spectrometry imaging (MSI) is able to simultaneously record the distributions of
hundreds of molecules directly from tissue. Rapid direct tissue analysis is essential for MSI …
hundreds of molecules directly from tissue. Rapid direct tissue analysis is essential for MSI …
A recommended and verified procedure for in situ tryptic digestion of formalin‐fixed paraffin‐embedded tissues for analysis by matrix‐assisted laser desorption …
Matrix‐assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is a
molecular imaging technology uniquely capable of untargeted measurement of proteins …
molecular imaging technology uniquely capable of untargeted measurement of proteins …
Antigen retrieval and its effect on the MALDI-MSI of lipids in formalin-fixed paraffin-embedded tissue
Formalin-fixed paraffin-embedded (FFPE) tissue represents the primary source of clinical
tissue and is routinely used in MALDI-MSI studies. However, it is not particularly suitable for …
tissue and is routinely used in MALDI-MSI studies. However, it is not particularly suitable for …
Applications of spatially resolved omics in the field of endocrine tumors
Y Hou, Y Gao, S Guo, Z Zhang, R Chen… - Frontiers in …, 2023 - frontiersin.org
Endocrine tumors derive from endocrine cells with high heterogeneity in function, structure
and embryology, and are characteristic of a marked diversity and tissue heterogeneity …
and embryology, and are characteristic of a marked diversity and tissue heterogeneity …
Feasibility of MALDI-MSI-Based Proteomics Using Bouin-Fixed Pathology Samples: Untap** the Goldmine of Nephropathology Archives
G Bindi, L Pagani, J Ceku, GS de Oliveira… - Journal of Proteome …, 2024 - ACS Publications
The application of innovative spatial proteomics techniques, such as those based upon
matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) …
matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) …