Metatranscriptomic analysis to define the Secrebiome, and 16S rRNA profiling of the gut microbiome in obesity and metabolic syndrome of Mexican children

L Gallardo-Becerra, F Cornejo-Granados… - Microbial cell …, 2020 - Springer
Background In the last decade, increasing evidence has shown that changes in human gut
microbiota are associated with diseases, such as obesity. The excreted/secreted proteins …

Elucidation of Akkermansia muciniphila Probiotic Traits Driven by Mucin Depletion

J Shin, JR Noh, DH Chang, YH Kim, MH Kim… - Frontiers in …, 2019 - frontiersin.org
Akkermansia muciniphila is widely considered a next-generation beneficial microbe. This
bacterium resides in the mucus layer of its host and regulates intestinal homeostasis and …

Progresses on bacterial secretomes enlighten research on Mycoplasma secretome

M Zubair, FA Khan, H Menghwar, M Faisal… - Microbial …, 2020 - Elsevier
Bacterial secretome is a comprehensive catalog of bacterial proteins that are released or
secreted outside the cells. They offer a number of factors that possess several significant …

Comparative systems analysis of the secretome of the opportunistic pathogen Aspergillus fumigatus and other Aspergillus species

RP Vivek-Ananth, K Mohanraj, M Vandanashree… - Scientific reports, 2018 - nature.com
Aspergillus fumigatus and multiple other Aspergillus species cause a wide range of lung
infections, collectively termed aspergillosis. Aspergilli are ubiquitous in environment with …

Development of multi-epitope based subunit vaccine against Mycobacterium Tuberculosis using immunoinformatics approach

S Kumari R, G Sethi, R Krishna - Journal of Biomolecular Structure …, 2024 - Taylor & Francis
The etiological agent of tuberculosis (TB), Mycobacterium tuberculosis, is a deadly pathogen
that adapts to thrive within the host. Since 2020, the COVID-19 pandemic has had colossal …

[HTML][HTML] Proteogenomics in aid of host–pathogen interaction studies: a bacterial perspective

U Fels, K Gevaert, P Van Damme - Proteomes, 2017 - mdpi.com
By providing useful tools to study host–pathogen interactions, next-generation omics has
recently enabled the study of gene expression changes in both pathogen and infected host …

Genome based screening of epitope ensemble vaccine candidates against dreadful visceral leishmaniasis using immunoinformatics approach

G Singh, M Pritam, M Banerjee, AK Singh… - Microbial …, 2019 - Elsevier
Visceral leishmaniasis (VL) is a dreadful protozoan disease caused by Leishmania
donovani that severely affects huge populations in tropical and sub-tropical regions. The …

[HTML][HTML] Targeted RNA-Seq Reveals the M. tuberculosis Transcriptome from an In Vivo Infection Model

F Cornejo-Granados, G López-Leal, DA Mata-Espinosa… - Biology, 2021 - mdpi.com
Simple Summary High-throughput sequencing techniques such as RNA-seq allow a more
detailed characterization of the gene expression profile during in vivo infections. However …

[HTML][HTML] Secret-AAR: a web server to assess the antigenic density of proteins and homology search against bacterial and parasite secretome proteins

F Cornejo-Granados, JM Hurtado-Ramírez… - Genomics, 2019 - Elsevier
The secretome refers to all the Excreted/Secreted (ES) proteins of a cell, and these are
involved in critical biological processes, such as cell-cell communication, and host immune …

Clinical and pathological characteristics associated with the presence of the IS6110 Mycobacterim tuberculosis transposon in neoplastic cells from non-small cell …

O Arrieta, C Molina-Romero, F Cornejo-Granados… - Scientific reports, 2022 - nature.com
Lung cancer (LC) and pulmonary tuberculosis (TB) are the deadliest neoplastic and
bacterial infectious diseases worldwide, respectively. Clinicians and pathologists have long …