Autologous chimeric antigen receptor (CAR) T cells have changed the therapeutic
landscape in haematological malignancies. Nevertheless, the use of allogeneic CAR T cells …

Inherited retinal diseases (IRDs) are a clinically complex and heterogenous group of visual
impairment phenotypes caused by pathogenic variants in at least 277 nuclear and …

The traditional healthcare system is at the doorstep for entering into the arena of molecular
medicine. The enormous knowledge and ongoing research have now been able to …

This last decade, chimeric antigen receptor (CAR) T-cell therapy has become a real
treatment option for patients with B-cell malignancies, while multiple efforts are being made …

The adoptive transfer of genetically engineered T cells with cancer-targeting receptors has
shown tremendous promise for eradicating tumors in clinical trials. This form of cellular …

Introduction: The discovery of gene editing techniques has opened a new era within the field
of biology and enabled scientists to manipulate nucleic acid molecules. CRISPR-Cas9 …

Plant synthetic biology is a rapidly growing field of science which is expected to significantly
contribute to the food, fiber, and fuel deficit because of fast increasing world population. By …

The idea of using the effector immune cells to specifically fight cancer has recently evolved
into an exciting concept of adoptive cell therapies. Indeed, genetically engineered T cells …

Genome editing (GE) is a mode of gene modification to develop elite crop varieties
expressing desirable traits. There are different GE technologies which could be …

The biosynthetic potential of life forms can be reinvigorated by genome manipulation and
construction of genetic circuits and complex regulatory networks to program new functions in …