Recent advances in the identification of biosynthetic genes and gene clusters of the polyketide-derived pathways for anthraquinone biosynthesis and biotechnological …

NK Mund, E Čellárová - Biotechnology Advances, 2023 - Elsevier
Natural anthraquinones are represented by a large group of compounds. Some of them are
widespread across the kingdoms, especially in bacteria, fungi and plants, while the others …

The latest research progress: active components of Traditional Chinese medicine as promising candidates for ovarian cancer therapy

X Zhang, X Wei, L Shi, H Jiang, F Ma, Y Li, C Li… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Ovarian cancer ranks the first in the mortality of
gynecological tumors. Because there are no obvious symptoms in the early stage of ovarian …

WenTongGanPi decoction alleviates diarrhea-predominant irritable bowel syndrome by improving intestinal barrier

Y Li, Y Chen, Z Liao, Y Liu, C Liu, W Yang, J Bai… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance WenTongGanPi Decoction (WTGPD) is a
representative medical practice of the Fuyang School of Traditional Chinese Medicine …

Reliable and consistent genotype selection for leaf biomass and natural sennosides yield across multi-environments in Senna (Senna alexandrina Mill)

A Kumar, AK Gupta, S Siddiqui, AC Jnanesha… - Ecological Genetics and …, 2024 - Elsevier
The relationship between genotype and season significantly hinders the development of
stable genotype selection and improved genotypes for senna breeding programs. This study …

Exploring characteristics of value-added production of anthraquinones in rhubarb via fermentation: Compartmental modelling and molecular docking analysis

G Sobremisana, R Ferrer, AR Carpio, LL Tayo… - Journal of the Taiwan …, 2023 - Elsevier
Background Rhubarb is an anthraquinone-rich herb with extensive pharmacological
properties. The study adopted compartmental modeling, metagenomic analysis, and …

A novel purgative mechanism of multiflorin A involves changing intestinal glucose absorption and permeability

Z Zhao, X Zuo, C Han, Y Zhang, J Zhao, Y Wang… - Phytomedicine, 2023 - Elsevier
Abstract Background Multiflorin A (MA) is a potential active ingredient of traditional herbal
laxative, Pruni semen, with unusual purgative activity and an unclear mechanism, and …

Machine learning-assisted optimized production of quorum quenching anthraquinones in rhubarb

G Sobremisana, LL Tayo, PW Tsai, CC Hsueh… - Journal of the Taiwan …, 2024 - Elsevier
Background This first attempt study focused on assessing the quorum quenching (QQ)
capabilities of four keystone anthraquinones—chrysophanol, emodin, aloe emodin, and …

[HTML][HTML] A comprehensive perspective of traditional Arabic or Islamic medicinal plants as an adjuvant therapy against COVID-19

SI Ahmed, S Jamil, H Ismatullah, R Hussain… - Saudi Journal of …, 2023 - Elsevier
COVID-19 is a pulmonary disease caused by SARS-CoV-2. More than 200 million
individuals are infected by this globally. Pyrexia, coughing, shortness of breath, headaches …

The application of rhubarb concoctions in traditional Chinese medicine and its compounds, processing methods, pharmacology, toxicology and clinical research

Y Wen, PJ Yan, PX Fan, SS Lu, MY Li, XY Fu… - Frontiers in …, 2024 - frontiersin.org
Objective This study reviews the development of rhubarb processing and the current status
of pharmacological research. We summarized the effects of different processing methods on …

Sennoside A restrains TRAF6 level to modulate ferroptosis, inflammation and cognitive impairment in aging mice with Alzheimer's Disease

X Li, X Wang, B Huang, R Huang - International immunopharmacology, 2023 - Elsevier
Background Alzheimer's disease (AD) is a common neurodegenerative disease and a
momentous cause of dementia in the elderly. Sennoside A (SA) is an anthraquinone …