COVID-19 mechanisms in the human body—What we know so far
More than one and a half years have elapsed since the commencement of the coronavirus
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …
Effects of SARS-CoV-2 on cardiovascular system: the dual role of angiotensin-converting enzyme 2 (ACE2) as the virus receptor and homeostasis regulator-review
A Aleksova, G Gagno, G Sinagra, AP Beltrami… - International journal of …, 2021 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) is the entry receptor for severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), the cause of Coronavirus Disease-2019 (COVID …
syndrome coronavirus-2 (SARS-CoV-2), the cause of Coronavirus Disease-2019 (COVID …
[HTML][HTML] Epigenome-wide association study of COVID-19 severity with respiratory failure
Background Patients infected with the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …
Antitarget, anti-SARS-CoV-2 leads, drugs, and the drug discovery–genetics alliance perspective
The most advanced antiviral molecules addressing major SARS-CoV-2 targets (Main
protease, Spike protein, and RNA polymerase), compared with proteins of other human …
protease, Spike protein, and RNA polymerase), compared with proteins of other human …
Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control …
K Schönfelder, K Breuckmann, C Elsner… - Frontiers in …, 2021 - frontiersin.org
The transmembrane serine protease 2 (TMPRSS2) is the major host protease that enables
entry of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) into host …
entry of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) into host …
Polymorphisms in ACE1, TMPRSS2, IFIH1, IFNAR2, and TYK2 Genes Are Associated with Worse Clinical Outcomes in COVID-19
Although advanced age, male sex, and some comorbidities impact the clinical course of
COVID-19, these factors only partially explain the inter-individual variability in disease …
COVID-19, these factors only partially explain the inter-individual variability in disease …
Human genetic basis of coronavirus disease 2019
H Deng, X Yan, L Yuan - Signal transduction and targeted therapy, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in considerable …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in considerable …
Host gene variability and SARS-CoV-2 infection: A review article
SARS-CoV-2 is a global threat that influenced healthcare systems around the world. This
virus caused an infection in humans with different clinical signs and syndromes, severity …
virus caused an infection in humans with different clinical signs and syndromes, severity …
Common variants at 21q22. 3 locus influence MX1 and TMPRSS2 gene expression and susceptibility to severe COVID-19
The established risk factors of coronavirus disease 2019 (COVID-19) are advanced age,
male sex, and comorbidities, but they do not fully explain the wide spectrum of disease …
male sex, and comorbidities, but they do not fully explain the wide spectrum of disease …
The impact of ACE and ACE2 gene polymorphisms in pulmonary diseases including COVID-19
Chronic and acute respiratory diseases pose a major problem for public health worldwide
due to the high morbidity and mortality rates, while treatment options remain mostly …
due to the high morbidity and mortality rates, while treatment options remain mostly …