Insights and implications of sexual dimorphism in osteoporosis

YY Zhang, N **e, XD Sun, EC Nice, YC Liou, C Huang… - Bone research, 2024 - nature.com
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk

K Maiese - Frontiers in immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

Estrogen-immuno-neuromodulation disorders in menopausal depression

Y Zhang, X Tan, C Tang - Journal of neuroinflammation, 2024 - Springer
A significant decrease in estrogen levels puts menopausal women at high risk for major
depression, which remains difficult to cure despite its relatively clear etiology. With the …

Cellular metabolism: a fundamental component of degeneration in the nervous system

K Maiese - Biomolecules, 2023 - mdpi.com
It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …

[HTML][HTML] Molecular mechanisms of the anti-inflammatory effects of epigallocatechin 3-gallate (EGCG) in LPS-activated BV-2 microglia cells

A Payne, E Taka, GM Adinew, KFA Soliman - Brain sciences, 2023 - mdpi.com
Brain Sciences | Free Full-Text | Molecular Mechanisms of the Anti-Inflammatory Effects of
Epigallocatechin 3-Gallate (EGCG) in LPS-Activated BV-2 Microglia Cells Next Article in …

The metabolic basis for nervous system dysfunction in alzheimer's disease, parkinson's disease, and huntington's disease

K Maiese - Current neurovascular research, 2023 - benthamdirect.com
Disorders of metabolism affect multiple systems throughout the body but may have the
greatest impact on both central and peripheral nervous systems. Currently available …

[HTML][HTML] Aging, sex, metabolic and life experience factors: Contributions to neuro-inflammaging in Alzheimer's disease research

PH Singhaarachchi, P Antal, F Calon… - Neuroscience & …, 2024 - Elsevier
Alzheimer's disease (AD) is prevalent around the world, yet our understanding of the
disease is still very limited. Recent work suggests that the cornerstone of AD may include the …

[PDF][PDF] The role of estrogen therapy as a protective factor for Alzheimer's disease and dementia in postmenopausal women: a comprehensive review of the literature

N Ali, R Sohail, SR Jaffer, S Siddique, B Kaya… - Cureus, 2023 - cureus.com
The complete cessation of menstruation for 12 months with associated vasomotor symptoms
is termed menopause. Apart from playing a role in reproduction, estrogen significantly …

The role of NF-κB signaling pathway in reactive astrocytes among neurodegeneration after methamphetamine exposure by integrated bioinformatics

K Li, H Ling, X Wang, Q **e, C Gu, W Luo… - Progress in Neuro …, 2024 - Elsevier
Background Methamphetamine (METH) is a highly addictive stimulant that has become one
of the top five risk substances cause deaths from substance abuse. METH exposure …

[HTML][HTML] AdipoRon's Impact on Alzheimer's Disease—A Systematic Review and Meta-Analysis

SM Barbalho, LF Laurindo… - International Journal of …, 2025 - mdpi.com
Alzheimer's disease (AD) remains a leading cause of cognitive decline and mortality
worldwide, characterized by neurodegeneration, synaptic deficiencies, and …