Calcific aortic stenosis

BR Lindman, MA Clavel, P Mathieu, B Iung… - Nature reviews Disease …, 2016 - nature.com
Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed
countries. It is characterized by progressive fibro-calcific remodelling and thickening of the …

2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task …

RA Nishimura, CM Otto, RO Bonow… - Journal of the American …, 2014 - jacc.org
The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through November 2012, and other …

2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint …

Writing Committee Members, CM Otto… - Journal of the American …, 2021 - jacc.org
The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

Aortic-valve stenosis—from patients at risk to severe valve obstruction

CM Otto, B Prendergast - New England Journal of Medicine, 2014 - Mass Medical Soc
Aortic-Valve Stenosis — From Patients at Risk to Severe Valve Obstruction | New England Journal
of Medicine Skip to main content Access provided by Charite - Universitaetsmedizin Berlin The …

Vascular calcification in CKD-MBD: Roles for phosphate, FGF23, and Klotho

S Yamada, CM Giachelli - Bone, 2017 - Elsevier
Vascular calcification (VC) is highly prevalent in aging, diabetes mellitus, and chronic kidney
disease (CKD). VC is a strong predictor of cardiovascular morbidity and mortality in the CKD …

Association between cardiovascular risk factors and aortic stenosis: the CANHEART aortic stenosis study

AT Yan, M Koh, KK Chan, H Guo, DA Alter… - Journal of the American …, 2017 - jacc.org
Background: Few longitudinal studies have delineated the association between traditional
cardiovascular risk factors and development of aortic stenosis (AS). Objectives: The authors …

Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease

KE Yutzey, LL Demer, SC Body… - … , and vascular biology, 2014 - Am Heart Assoc
Calcific aortic valve disease (CAVD) is increasingly prevalent worldwide with significant
morbidity and mortality. Therapeutic options beyond surgical valve replacement are …

Knowledge gaps in cardiovascular care of the older adult population: a scientific statement from the American Heart Association, American College of Cardiology, and …

MW Rich, DA Chyun, AH Skolnick, KP Alexander… - Journal of the American …, 2016 - jacc.org
The incidence and prevalence of most cardiovascular disorders increase with age, and
cardiovascular disease is the leading cause of death and major disability in adults≥ 75 …

Futility, benefit, and transcatheter aortic valve replacement

BR Lindman, KP Alexander, PT O'Gara… - JACC: Cardiovascular …, 2014 - jacc.org
Transcatheter aortic valve replacement (TAVR) is a transformative innovation that provides
treatment for high or prohibitive surgical risk patients with symptomatic severe aortic stenosis …

LncRNA MALAT1 sponges miR-204 to promote osteoblast differentiation of human aortic valve interstitial cells through up-regulating Smad4

X **ao, T Zhou, S Guo, C Guo, Q Zhang, N Dong… - International journal of …, 2017 - Elsevier
Background Emerging evidences have indicated that long non-coding RNAs (lncRNAs) play
vital roles in cardiovascular physiology and pathology. The lncRNA MALAT1, a highly …