Kidney organoids: steps towards better organization and function
Kidney organoids—3D representations of kidneys made either from pluripotent or tissue
stem cells—have been available for well over a decade. Their application could confer …
stem cells—have been available for well over a decade. Their application could confer …
Kidney Disease Modeling with Organoids and Organs-on-Chips
S Musah, R Bhattacharya… - Annual Review of …, 2024 - annualreviews.org
Kidney disease is a global health crisis affecting more than 850 million people worldwide. In
the United States, annual Medicare expenditures for kidney disease and organ failure …
the United States, annual Medicare expenditures for kidney disease and organ failure …
An ultrathin membrane mediates tissue-specific morphogenesis and barrier function in a human kidney chip
Organ-on-chip (OOC) systems are revolutionizing tissue engineering by providing dynamic
models of tissue structure, organ-level function, and disease phenotypes using human cells …
models of tissue structure, organ-level function, and disease phenotypes using human cells …
Ultrastructural characterization of maturing iPSC‐derived nephron structures upon transplantation
LE Wiersma, MC Avramut, AJ Koster… - Microscopy …, 2024 - Wiley Online Library
Pluripotent stem cell‐derived kidney organoids hold great promise as a potential auxiliary
transplant tissue for individuals with end‐stage renal disease and as a platform for studying …
transplant tissue for individuals with end‐stage renal disease and as a platform for studying …
Straddling the Line Between In Vitro and Ex Vivo Investigations
L Klein, DW Hutmacher - Tissue Engineering Part C: Methods, 2024 - liebertpub.com
Tissue engineering research fundamentally relies on experiments to advance knowledge,
utilizing various models for research on both humans and animals. With scientific progress …
utilizing various models for research on both humans and animals. With scientific progress …
[HTML][HTML] A human stem cell-derived model reveals pathologic extracellular matrix remodeling in diabetic podocyte injury
Y Roye, C Miller, TD Kalejaiye, S Musah - Matrix Biology Plus, 2024 - Elsevier
Diabetic nephropathy results from chronic (or uncontrolled) hyperglycemia and is the
leading cause of kidney failure. The kidney's glomerular podocytes are highly susceptible to …
leading cause of kidney failure. The kidney's glomerular podocytes are highly susceptible to …
Biomaterials for Artificial Organs and Organoids-A Comprehensive review
K Praveena, M Manjunatha, A Awasthi… - E3S Web of …, 2024 - e3s-conferences.org
The technological development of biomaterials used in forming artificial organs and
organoids indicates a revolutionary area within biomedical engineering and the field of …
organoids indicates a revolutionary area within biomedical engineering and the field of …