The significance of beige and brown fat in humans

FW Kiefer - Endocrine connections, 2017 - ec.bioscientifica.com
Promotion of brown adipose tissue (BAT) activity or browning of white adipose tissue has
shown great potential as anti-obesity strategy in numerous preclinical models. The discovery …

Magnetic resonance imaging techniques for brown adipose tissue detection

M Wu, D Junker, RT Branca… - Frontiers in …, 2020 - frontiersin.org
Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) methods
can non-invasively assess brown adipose tissue (BAT) structure and function. Recently, MRI …

Brown adipose tissue: a new potential target for glucagon-like peptide 1 receptor agonists in the treatment of obesity

T Hropot, R Herman, A Janez, L Lezaic… - International Journal of …, 2023 - mdpi.com
Adipose tissue can be divided into white adipose tissue (WAT), brown adipose tissue (BAT),
and beige adipose tissue, according to the differences in morphology. WAT acts as a buffer …

Recent advances in the detection of brown adipose tissue in adult humans: a review

FJ Ong, BA Ahmed, SM Oreskovich, DP Blondin… - Clinical …, 2018 - portlandpress.com
The activation of brown adipose tissue (BAT) is associated with reductions in circulating
lipids and glucose in rodents and contributes to energy expenditure in humans indicating …

MR signal-fat-fraction analysis and T2* weighted imaging measure BAT reliably on humans without cold exposure

M Holstila, M Pesola, T Saari, K Koskensalo, J Raiko… - Metabolism, 2017 - Elsevier
Objective Brown adipose tissue (BAT) is compositionally distinct from white adipose tissue
(WAT) in terms of triglyceride and water content. In adult humans, the most significant BAT …

Cold exposure induces dynamic, heterogeneous alterations in human brown adipose tissue lipid content

CL Coolbaugh, BM Damon, EC Bush, EB Welch… - Scientific Reports, 2019 - nature.com
Brown adipose tissue undergoes a dynamic, heterogeneous response to cold exposure that
can include the simultaneous synthesis, uptake, and oxidation of fatty acids. The purpose of …

A new personalized cooling protocol to activate brown adipose tissue in young adults

B Martinez-Tellez, G Sanchez-Delgado… - Frontiers in …, 2017 - frontiersin.org
Brown adipose tissue (BAT) activity is induced when humans are exposed to cold.
Therefore, cold exposure prior to the 18F-FDG-PET/CT scan is used as a tool to quantify …

[HTML][HTML] Twelve weeks of exenatide treatment increases [18F] fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy …

LGM Janssen, KJ Nahon, KFM Bracké… - Metabolism, 2020 - Elsevier
Aims/hypothesis Brown adipose tissue (BAT) improves energy metabolism by combusting
glucose and lipids into heat. Agonism of the glucagon-like peptide-1 receptor (GLP-1R) …

Association of proton density fat fraction in adipose tissue with imaging-based and anthropometric obesity markers in adults

D Franz, D Weidlich, F Freitag, C Holzapfel… - International Journal of …, 2018 - nature.com
Results: Mean supraclavicular PDFF was 75.3±4.7%(range 65.4–83.8%) and mean gluteal
PDFF was 89.7±2.9%(range 82.2-94%), resulting in a significant difference (P< 0.0001) …

Magnetic resonance imaging of obesity and metabolic disorders: Summary from the 2019 ISMRM Workshop

HH Hu, RT Branca, D Hernando… - Magnetic resonance …, 2020 - Wiley Online Library
More than 100 attendees from Australia, Austria, Belgium, Canada, China, Germany, Hong
Kong, Indonesia, Japan, Malaysia, the Netherlands, the Philippines, Republic of Korea …