Background Inflammation in the lung is the body's natural response to injury. It acts to
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …

The advances in genetics and biochemistry that have taken place over the last 10 years led
to significant advances in experimental and clinical immunology. In turn, this has led to the …

New regenerative materials and approaches need to be assessed through reliable and
comparable methods for rapid translation to the clinic. There is a considerable need for …

Inflammation is a complex, multi-scale biologic response to stress that is also required for
repair and regeneration after injury. Despite the repository of detailed data about the cellular …

Sepsis is a clinical syndrome characterized by a multisystem response to a microbial
pathogenic insult consisting of a mosaic of interconnected biochemical, cellular, and organ …

Simulations using various methods can shed insight into the pathophysiology of the acute
inflammatory response and may lead to better design of clinical trials in sepsis and trauma. a …

Traumatic injury/hemorrhagic shock (T/HS) elicits an acute inflammatory response that may
result in death. Inflammation describes a coordinated series of molecular, cellular, tissue …

Significance: Traumatic injury elicits a complex, dynamic, multidimensional inflammatory
response that is intertwined with complications such as multiple organ dysfunction and …

The purpose of this review is to provide a brief overview of bioreactor‐based culture systems
as alternatives to conventional two‐and three‐dimensional counterparts. The role …

The pharmaceutical industry is almost boundless in its ability to supply new drug therapies,
but how does one decide which are the best medicines to use within restricted budgets …