Artificial intelligence in pharmacology research and practice

M Van der Lee, JJ Swen - Clinical and Translational Science, 2023 - Wiley Online Library
In recent years, the use of artificial intelligence (AI) in health care has risen steadily,
including a wide range of applications in the field of pharmacology. AI is now used …

[HTML][HTML] Trends and opportunities in computable clinical phenoty**: a sco** review

T He, A Belouali, J Patricoski, H Lehmann… - Journal of Biomedical …, 2023 - Elsevier
Identifying patient cohorts meeting the criteria of specific phenotypes is essential in
biomedicine and particularly timely in precision medicine. Many research groups deliver …

Measurement of lipid flux to advance translational research: evolution of classic methods to the future of precision health

AF Salvador, CR Shyu, EJ Parks - Experimental & Molecular Medicine, 2022 - nature.com
Over the past 70 years, the study of lipid metabolism has led to important discoveries in
identifying the underlying mechanisms of chronic diseases. Advances in the use of stable …

[PDF][PDF] Harnessing the power of AI in pharmacokinetics and pharmacodynamics: a comprehensive review

V Pawar, A Patil, F Tamboli, D Gaikwad… - International Journal …, 2023 - researchgate.net
Personalized medicine, medication discovery, and development might all benefit greatly
from AI's incorporation into pharmacokinetics and pharmacodynamics. Target identification …

Explainable ai in drug sensitivity prediction on cancer cell lines

IS Gillani, M Shahzad, A Mobin… - … on Emerging Trends …, 2022 - ieeexplore.ieee.org
Explainable Artificial Intelligence (XAI) is a field that develops ways to explain predictions
made by AI models. In this paper XAI which is a multifaceted approach is discussed which is …

Drug repositioning and subgroup discovery for precision medicine implementation in triple negative breast cancer

Z Al-Taie, M Hannink, J Mitchem, C Papageorgiou… - Cancers, 2021 - mdpi.com
Simple Summary The heterogeneity of complicated diseases like cancer negatively affects
patients' responses to treatment. Finding homogeneous subgroups of patients within the …

MIFNet: multimodal interactive fusion network for medication recommendation

J Huo, Z Hong, M Chen, Y Duan - The Journal of Supercomputing, 2024 - Springer
Medication recommendation aims to provide clinicians with safe medicine combinations for
the treatment of patients. Existing medication recommendation models are built based on …

[HTML][HTML] Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU

I Vagliano, MY Kingma, DA Dongelmans… - Computers in Biology …, 2023 - Elsevier
Background–Subgroup discovery (SGD) is the automated splitting of the data into complex
subgroups. Various SGD methods have been applied to the medical domain, but none have …

GraphIX: Graph-based In silico XAI (explainable artificial intelligence) for drug repositioning from biopharmaceutical network

A Takagi, M Kamada, E Hamatani, R Kojima… - arxiv preprint arxiv …, 2022 - arxiv.org
Drug repositioning holds great promise because it can reduce the time and cost of new drug
development. While drug repositioning can omit various R&D processes, confirming …

[HTML][HTML] Comparison of Medical Opinions About the Decrease in Autopsies in Mexican Hospitals Using Data Mining

A Olmos-Vallejo, L Rodríguez-Mazahua… - Electronics, 2024 - mdpi.com
Subgroup discovery (SD) is a data mining technique that allows us to obtain the properties
of each element given a particular population; these properties are of interest for a specific …