The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …

Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …

Advances in cardiovascular research have identified oxidative stress as an important
pathophysiological pathway in the development and progression of heart failure. Oxidative …

Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Disorders characterized by ischemia/reperfusion (I/R), such as myocardial infarction, stroke,
and peripheral vascular disease, continue to be among the most frequent causes of …

Oxidative stress, defined as an excess production of reactive oxygen species (ROS) relative
to antioxidant defense, has been shown to play an important role in the pathophysiology of …

Hematopoietic stem cells (HSCs) reside in hypoxic niches within bone marrow and cord
blood. Yet, essentially all HSC studies have been performed with cells isolated and …

The function of mitochondrial fusion and fission is one of the important factors causing
ischemia-reperfusion (I/R) injury in diabetic myocardium. Aldehyde dehydrogenase 2 …

The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Proangiogenesis is generally regarded as an effective approach for treating ischemic heart
disease. Vascular endothelial growth factor (VEGF)‐A is a strong and essential …