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A review of parameter settings for invasive and non-invasive vagus nerve stimulation (VNS) applied in neurological and psychiatric disorders
Vagus nerve stimulation (VNS) is an established form of neuromodulation with a long history
of promising applications. Earliest reports of VNS in the literature date to the late 1800's in …
of promising applications. Earliest reports of VNS in the literature date to the late 1800's in …
Targeted vagus nerve stimulation for rehabilitation after stroke
Stroke is a leading cause of disability worldwide, and in approximately 60% of individuals,
upper limb deficits persist 6 months after stroke. These deficits adversely affect the functional …
upper limb deficits persist 6 months after stroke. These deficits adversely affect the functional …
[HTML][HTML] Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement
Vagus nerve stimulation (VNS) is a neuromodulation therapy for a broad and expanding set
of neurologic conditions. However, the mechanism through which VNS influences central …
of neurologic conditions. However, the mechanism through which VNS influences central …
Parametric characterization of neural activity in the locus coeruleus in response to vagus nerve stimulation
Vagus nerve stimulation (VNS) has emerged as a therapy to treat a wide range of
neurological disorders, including epilepsy, depression, stroke, and tinnitus. Activation of …
neurological disorders, including epilepsy, depression, stroke, and tinnitus. Activation of …
Safety, feasibility, and efficacy of vagus nerve stimulation paired with upper-limb rehabilitation after ischemic stroke
Background and Purpose—Recent animal studies demonstrate that vagus nerve stimulation
(VNS) paired with movement induces movement-specific plasticity in motor cortex and …
(VNS) paired with movement induces movement-specific plasticity in motor cortex and …
[HTML][HTML] Vagus nerve stimulation induces widespread cortical and behavioral activation
Vagus nerve stimulation (VNS) is used for management of a variety of neurological
conditions, although the therapeutic mechanisms are not fully understood. Accumulating …
conditions, although the therapeutic mechanisms are not fully understood. Accumulating …
Vagus nerve stimulation paired with tones for the treatment of tinnitus: a prospective randomized double-blind controlled pilot study in humans
The aim of the pilot study was to evaluate the effect of Vagus Nerve Stimulation (VNS) paired
with sounds in chronic tinnitus patients. All participants were implanted and randomized to a …
with sounds in chronic tinnitus patients. All participants were implanted and randomized to a …
[HTML][HTML] How to fail with paired VNS therapy
Vagus nerve stimulation (VNS) has gained enormous traction as a promising bioelectronic
therapy. In particular, the delivery of VNS paired with training to promote neural changes has …
therapy. In particular, the delivery of VNS paired with training to promote neural changes has …
Norepinephrine and serotonin are required for vagus nerve stimulation directed cortical plasticity
Vagus nerve stimulation (VNS) paired with forelimb training drives robust, specific
reorganization of movement representations in the motor cortex. This effect is hypothesized …
reorganization of movement representations in the motor cortex. This effect is hypothesized …
Closed-loop neuromodulation restores network connectivity and motor control after spinal cord injury
Recovery from serious neurological injury requires substantial rewiring of neural circuits.
Precisely-timed electrical stimulation could be used to restore corrective feedback …
Precisely-timed electrical stimulation could be used to restore corrective feedback …