MicroRNA-155: a master regulator of inflammation

G Mahesh, R Biswas - Journal of Interferon & Cytokine Research, 2019 - liebertpub.com
MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (∼ 22
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …

The epigenetics of maternal cigarette smoking during pregnancy and effects on child development

VS Knopik, MA Maccani, S Francazio… - Development and …, 2012 - cambridge.org
The period of in utero development is one of the most critical windows during which adverse
intrauterine conditions and exposures can influence the growth and development of the …

Group 3 pulmonary hypertension: from bench to bedside

N Singh, P Dorfmüller, OA Shlobin… - Circulation …, 2022 - ahajournals.org
Pulmonary hypertension (PH) because of chronic lung disease is categorized as Group 3
PH in the most recent classification system. Prevalence of these diseases is increasing over …

Experimental validation of miRNA targets

DE Kuhn, MM Martin, DS Feldman, AV Terry Jr… - Methods, 2008 - Elsevier
MicroRNAs are natural, single-stranded, small RNA molecules that regulate gene
expression by binding to target mRNAs and suppress its translation or initiate its …

Cellular reservoirs of HIV-1 and their role in viral persistence

A Alexaki, Y Liu, B Wigdahl - Current HIV research, 2008 - ingentaconnect.com
A major obstacle in human immunodeficiency virus type 1 (HIV-1) eradication is the ability of
the virus to remain latent in a subpopulation of the cells it infects. Latently infected cells can …

The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members

TA Farazi, SA Juranek, T Tuschl - 2008 - journals.biologists.com
Several distinct classes of small RNAs, some newly identified, have been discovered to play
important regulatory roles in diverse cellular processes. These classes include siRNAs …

Maturation of human oocytes in vitro and their developmental competence

A Trounson, C Anderiesz, G Jones - Reproduction, 2001 - rep.bioscientifica.com
Complete maturation of oocytes is essential for the developmental competence of embryos.
Any interventions in the growth phase of the oocyte and the follicle in the ovary will affect …

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

M Coiras, MR López-Huertas… - Nature Reviews …, 2009 - nature.com
HIV-1 can infect both activated and resting, non-dividing cells, following which the viral
genome can be permanently integrated into a host cell chromosome. Latent HIV-1 reservoirs …

Predicting later-life outcomes of early-life exposures

K Boekelheide, B Blumberg, RE Chapin… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: In utero exposure of the fetus to a stressor can lead to disease in later life.
Epigenetic mechanisms are likely mediators of later-life expression of early-life events …