Glycans are ubiquitous in nature, decorating our cells and serving as the initial points of
contact with any visiting entities. These glycan interactions are fundamental to host …

Target identification is crucial for drug screening and development because it can reveal the
mechanism of drug action and ensure the reliability and accuracy of the results. Chemical …

Inhibitor discovery for emerging drug-target proteins is challenging, especially when target
structure or active molecules are unknown. Here, we experimentally validate the broad utility …

Native mass spectrometry (nMS) screening of natural glycan libraries against glycan-binding
proteins (GBPs) is a powerful tool for ligand discovery. However, as the glycan …

Bovine casein was used as a model protein to explore the binding behavior of food matrix
with residual antibiotics. The interaction mechanism between casein and tetracycline (TC) …

Proteins, serving as the fundamental architects of biological processes, interact with ligands
to perform a myriad of functions essential for life. Designing functional ligand-binding …

We have used NMR experiments to explore the binding of selected glycans and
glycomimetics to the SARS CoV‐2 spike glycoprotein (S‐protein) and to its receptor binding …

Severe Acute Respiratory syndrome 2 (SARS-CoV-2) is a respiratory virus responsible for
coronavirus disease 19 (COVID-19) and the still ongoing and unprecedented global …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has had a major impact on
human life. This review highlights the versatile roles of both classical and modern structure …

Proteins, serving as the fundamental architects of biological processes, interact with ligands
to perform a myriad of functions essential for life. The design and optimization of ligand …