Coronary arterial disease is the most common cardiovascular disease. Myocardial ischemia-
reperfusion injury caused by the initial interruption of organ blood flow and subsequent …

Heart failure is a global public health problem that affects more than 26 million people
worldwide. The global burden of heart failure is growing and is expected to increase …

Autologous induced pluripotent stem cells (iPSCs) constitute an unlimited cell source for
patient-specific cell-based organ repair strategies. However, their generation and …

Aims Naturally secreted nanovesicles, known as exosomes, play important roles in stem cell-
mediated cardioprotection. We have previously demonstrated that atorvastatin (ATV) …

Rationale: Umbilical cord–derived mesenchymal stem cells (UC-MSC) are easily accessible
and expanded in vitro, possess distinct properties, and improve myocardial remodeling and …

Importance Stem cell therapy is a promising treatment strategy for patients with heart failure,
which accounts for more than 10% of deaths in the United States annually. Despite more …

Alginate biomaterial is widely utilized for tissue engineering and regeneration due to its
biocompatibility, non-thrombogenic nature, mild and physical gelation process, and the …

Rationale: Critical limb ischemia is a life-threatening complication of peripheral arterial
disease. In patients who are ineligible for revascularization procedures, there are few …

Aims Cardiopoietic cells, produced through cardiogenic conditioning of patients'
mesenchymal stem cells, have shown preliminary efficacy. The Congestive Heart Failure …

Background A promising approach to the treatment of chronic ischaemic heart disease and
congestive heart failure is the use of stem cells. The last decade has seen a plethora of …