Stimuli-responsive polydopamine-based smart materials

P Yang, F Zhu, Z Zhang, Y Cheng, Z Wang… - Chemical Society …, 2021 - pubs.rsc.org
Stimuli responsiveness has long been a fascinating feature of smart material design.
Polydopamine (PDA), a nature inspired polymeric pigment, exhibits excellent photo …

Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release

J Liu, H Cabral, P Mi - Advanced Drug Delivery Reviews, 2024 - Elsevier
The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …

Nanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics

C Xu, J Huang, Y Jiang, S He, C Zhang… - Nature Biomedical …, 2023 - nature.com
Molecular imaging via afterglow luminescence minimizes tissue autofluorescence and
increases the signal-to-noise ratio. However, the induction of afterglow requires the prior …

A photo-triggered self-accelerated nanoplatform for multifunctional image-guided combination cancer immunotherapy

X Kang, Y Zhang, J Song, L Wang, W Li, J Qi… - Nature …, 2023 - nature.com
Precise and efficient image-guided immunotherapy holds great promise for cancer
treatment. Here, we report a self-accelerated nanoplatform combining an aggregation …

Oncolytic mineralized bacteria as potent locally administered immunotherapeutics

C Wang, L Zhong, J Xu, Q Zhuang, F Gong… - Nature Biomedical …, 2024 - nature.com
Oncolytic bacteria can trigger innate immune activity. However, the antitumour efficacy of
inactivated bacteria is poor, and attenuated live bacteria pose substantial safety risks. Here …

Single atom catalysts remodel tumor microenvironment for augmented sonodynamic immunotherapy

B Geng, J Hu, X He, Z Zhang, J Cai, D Pan… - Advanced …, 2024 - Wiley Online Library
The immunosuppressive tumor microenvironment (TME) is a huge hurdle in immunotherapy.
Sono‐immunotherapy is a new treatment modality that can reverse immunosuppressive …

Light-triggered nanozymes remodel the tumor hypoxic and immunosuppressive microenvironment for ferroptosis-enhanced antitumor immunity

Z Fan, S Wu, H Deng, G Li, L Huang, H Liu - ACS nano, 2024 - ACS Publications
Cancer immunotherapy holds significant promise for addressing diverse malignancies.
Nevertheless, its efficacy remains constrained by the intricate tumor immunosuppressive …

Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Tumor‐microenvironment‐activated reactive oxygen species amplifier for enzymatic cascade cancer starvation/chemodynamic/immunotherapy

M Wang, M Chang, C Li, Q Chen, Z Hou… - Advanced …, 2022 - Wiley Online Library
At present, some progress has been made in the field of cancer theranostics based on
nanocatalysts (NCs), but achieving precise theranostics in response to the specific tumor …

Bioorthogonal-activated in situ vaccine mediated by a COF-based catalytic platform for potent cancer immunotherapy

M Sun, Z Liu, L Wu, J Yang, J Ren… - Journal of the American …, 2023 - ACS Publications
Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …