A fundamental function of the intestinal epithelium is to act as a barrier that limits interactions
between luminal contents such as the intestinal microbiota, the underlying immune system …

Mucosal surfaces are lined by epithelial cells. In the intestine, the epithelium establishes a
selectively permeable barrier that supports nutrient absorption and waste secretion while …

Congenital hearing loss (hearing loss that is present at birth) is one of the most prevalent
chronic conditions in children. In the majority of developed countries, neonatal hearing …

Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …

Endothelial tight junctions (TJs) regulate the transport of water, ions, and molecules through
the paracellular pathway, serving as an important barrier in blood vessels and maintaining …

The tight junction creates an intercellular barrier limiting paracellular movement of solutes
and material across epithelia. Currently many proteins have been identified as components …

The blood-retinal barrier (BRB) regulates transport across retinal capillaries maintaining
proper neural homeostasis and protecting the neural tissue from potential blood borne …

The blood–brain barrier (BBB) is a term used to describe a series of properties possessed
by the vasculature of the central nervous system (CNS) that tightly regulate the movement of …

Mucosal barriers separate self from non-self and are essential for life. These barriers, which
are the first line of defense against external pathogens, are formed by epithelial cells and the …

Little is known about the genetic changes that distinguish domestic cat populations from
their wild progenitors. Here we describe a high-quality domestic cat reference genome …