Cytokines in cancer immunotherapy
TA Waldmann - Cold Spring Harbor perspectives in …, 2018 - cshperspectives.cshlp.org
Cytokines that control the immune response were shown to have efficacy in preclinical
murine cancer models. Interferon (IFN)-α is approved for treatment of hairy cell leukemia …
murine cancer models. Interferon (IFN)-α is approved for treatment of hairy cell leukemia …
Persistent activation of pancreatic stellate cells creates a microenvironment favorable for the malignant behavior of pancreatic ductal adenocarcinoma
D Tang, D Wang, Z Yuan, X Xue… - … journal of cancer, 2013 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is one of the most common malignant tumors
with poor prognosis due to extremely high malignancy, low rate of eligibility for surgical …
with poor prognosis due to extremely high malignancy, low rate of eligibility for surgical …
Evaluating strategies to normalise biological replicates of Western blot data
Western blot data are widely used in quantitative applications such as statistical testing and
mathematical modelling. To ensure accurate quantitation and comparability between …
mathematical modelling. To ensure accurate quantitation and comparability between …
Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), induces formation of
granulomas, structures in which immune cells and bacteria colocalize. Macrophages are …
granulomas, structures in which immune cells and bacteria colocalize. Macrophages are …
Pancreatic cancer survival analysis defines a signature that predicts outcome
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the
US. Despite multiple large-scale genetic sequencing studies, identification of predictors of …
US. Despite multiple large-scale genetic sequencing studies, identification of predictors of …
The role of interferon-gamma and its receptors in gastrointestinal cancers
Gastrointestinal malignancies are the most prevalent type of cancer around the world. Even
though numerous studies have evaluated gastrointestinal malignancies, the actual …
though numerous studies have evaluated gastrointestinal malignancies, the actual …
Systems biology of JAK-STAT signalling in human malignancies
Originally implicated in the regulation of survival, proliferation and differentiation of
haematopoietic cells, the JAK-STAT pathway has also been linked to developmental …
haematopoietic cells, the JAK-STAT pathway has also been linked to developmental …
Cancer immunotherapy: diverse approaches and obstacles
Cancer immunotherapy approaches have progressed significantly during the last decade
due to the significant improvement of our understanding of immunologic evasion of …
due to the significant improvement of our understanding of immunologic evasion of …
Antitumor and chemosensitizing action of 3-bromopyruvate: implication of deregulated metabolism
Bromopyruvate (3-BP), brominated derivative of pyruvate, possesses strong antitumor
potential, owing to its ability to inhibit multiple target molecules crucial for survival of …
potential, owing to its ability to inhibit multiple target molecules crucial for survival of …
Serum biomarker panel diagnostics in pancreatic ductal adenocarcinoma: the clinical utility of soluble interleukins, IFN-γ, TNF-α and PD-1/PD-L1 in comparison to …
K Dorman, M Gerckens, S Kruger, K Krueger… - Journal of cancer …, 2023 - Springer
Purpose Novel biomarkers to better predict outcome and select the best therapeutic strategy
for the individual patient are necessary for pancreatic ductal adenocarcinoma (PDAC) …
for the individual patient are necessary for pancreatic ductal adenocarcinoma (PDAC) …