The pathological hallmarks of Parkinson's disease (PD) are the progressive loss of
dopaminergic neurons in the substantia nigra and the formation of Lewy bodies (LBs) in …

Parkinson's disease (PD) is characterized by motor dysfunctions including bradykinesia,
tremor at rest and motor instability. These symptoms are associated with the progressive …

Parkinson's disease (PD) is the second most prevalent neurodegenerative movement
disorder worldwide, which is primarily characterized by motor impairments. Even though …

Recordings and stimulations of neuronal electrical activity are topics of great interest in
neuroscience. Many recording techniques, and even treatment of neurological disorders …

An intronic hexanucleotide (GGGGCC) expansion in the C9orf72 gene is the most common
genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). In …

Abstract Bis (2-ethylhexyl) phthalate (DEHP) is the most common plasticizer. Previous
studies have shown DEHP treatment accelerates neurological degeneration, suggesting …

Features of ongoing experience are common across individuals and cultures. However,
certain people express specific patterns of thought to a greater extent than others …

Leucine-rich repeat kinase 2 (LRRK2) is a gene related to familial Parkinson's disease (PD).
It has been associated with nonmotor symptoms such as disturbances in the visual system …

Background Degeneration of the nigrostriatal dopaminergic pathway has been seen as a
significant cause of movement disability in Parkinson's disease (PD) patients. However, the …

LRRK2 mutations cause Parkinson's, but the molecular link from increased kinase activity to
pathological neurodegeneration remains undetermined. Previous in vitro assays indicate …