Hydrogenases
The reaction takes place at a specialized metal center that dramatically increases the acidity
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …
Second and outer coordination sphere effects in nitrogenase, hydrogenase, formate dehydrogenase, and CO dehydrogenase
Gases like H2, N2, CO2, and CO are increasingly recognized as critical feedstock in “green”
energy conversion and as sources of nitrogen and carbon for the agricultural and chemical …
energy conversion and as sources of nitrogen and carbon for the agricultural and chemical …
Structure and function of [NiFe] hydrogenases
Hydrogenases catalyze the reversible conversion of molecular hydrogen to protons and
electrons via a heterolytic splitting mechanism. The active sites of [NiFe] hydrogenases …
electrons via a heterolytic splitting mechanism. The active sites of [NiFe] hydrogenases …
Infrared Spectroscopy During Electrocatalytic Turnover Reveals the Ni‐L Active Site State During H2 Oxidation by a NiFe Hydrogenase
R Hidalgo, PA Ash, AJ Healy… - Angewandte Chemie …, 2015 - Wiley Online Library
A novel in situ IR spectroscopic approach is demonstrated for the characterization of
hydrogenase during catalytic turnover. E. coli hydrogenase 1 (Hyd‐1) is adsorbed on a high …
hydrogenase during catalytic turnover. E. coli hydrogenase 1 (Hyd‐1) is adsorbed on a high …
[HTML][HTML] Unusual structures and unknown roles of FeS clusters in metalloenzymes seen from a resonance Raman spectroscopic perspective
G Caserta, L Zuccarello, C Barbosa, CM Silveira… - Coordination Chemistry …, 2022 - Elsevier
The universe of known biological FeS clusters is constantly enlarging. Besides the
conventional, well described [2Fe–2S],[3Fe–4S] and cubane [4Fe–4S] clusters, novel …
conventional, well described [2Fe–2S],[3Fe–4S] and cubane [4Fe–4S] clusters, novel …
Protonation/reduction dynamics at the [4Fe–4S] cluster of the hydrogen-forming cofactor in [FeFe]-hydrogenases
The [FeFe]-hydrogenases of bacteria and algae are the most efficient hydrogen conversion
catalysts in nature. Their active-site cofactor (H-cluster) comprises a [4Fe–4S] cluster linked …
catalysts in nature. Their active-site cofactor (H-cluster) comprises a [4Fe–4S] cluster linked …
Hydride bridge in [NiFe]-hydrogenase observed by nuclear resonance vibrational spectroscopy
The metabolism of many anaerobes relies on [NiFe]-hydrogenases, whose characterization
when bound to substrates has proven non-trivial. Presented here is direct evidence for a …
when bound to substrates has proven non-trivial. Presented here is direct evidence for a …
Reversible [4Fe-3S] cluster morphing in an O2-tolerant [NiFe] hydrogenase
S Frielingsdorf, J Fritsch, A Schmidt, M Hammer… - Nature chemical …, 2014 - nature.com
Hydrogenases catalyze the reversible oxidation of H2 into protons and electrons and are
usually readily inactivated by O2. However, a subgroup of the [NiFe] hydrogenases …
usually readily inactivated by O2. However, a subgroup of the [NiFe] hydrogenases …
Cysteine SH and glutamate COOH contributions to [NiFe] hydrogenase proton transfer revealed by highly sensitive FTIR spectroscopy
Abstract A [NiFe] hydrogenase (H2ase) is a proton‐coupled electron transfer enzyme that
catalyses reversible H2 oxidation; however, its fundamental proton transfer pathway remains …
catalyses reversible H2 oxidation; however, its fundamental proton transfer pathway remains …
Proton transfer in the catalytic cycle of [NiFe] hydrogenases: insight from vibrational spectroscopy
PA Ash, R Hidalgo, KA Vincent - ACS catalysis, 2017 - ACS Publications
Catalysis of H2 production and oxidation reactions is critical in renewable energy systems
based around H2 as a clean fuel, but the present reliance on platinum-based catalysts is not …
based around H2 as a clean fuel, but the present reliance on platinum-based catalysts is not …